Home quarantine: A numerical evaluation of SARS-CoV-2 spread in a single-family house자가격리: 단독주택에서 SARS-CoV-2 확산 수치 평가Article Published on 2022-05-012022-09-11 Journal: Indoor air [Category] COVID19(2023년), SARS, 치료기술, [키워드] aerosol affected cause Concentration contagious Contamination coronavirus disease Coronavirus disease 2019 country COVID-19 Critical case critical cases droplet emission French home home quarantine hospital lack Numerical simulation parameter quarantine reduce response risk SARS-CoV-2 sick single-family house Spread Symptom the disease Transmission Transport Ventilation virus worldwide pandemic [DOI] 10.1111/ina.13035 PMC 바로가기 [Article Type] Article
An overview on inactivated and live-attenuated SARS-CoV-2 vaccines불활성화 및 약독화 SARS-CoV-2 백신에 대한 개요Review Published on 2022-05-012022-09-11 Journal: Journal of Clinical Laboratory Analysis [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse effects antigenic attenuated vaccine benefit Bharat Cell culture Cellular immune response China clinical trials component components coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine deaths effective Efficiency Features followed by Health Organization humoral Humoral and cellular immune responses immune responses inactivated Inactivated vaccine Infection landscape Phase 3 produced producing Record report review Safe SARS-CoV-2 SARS-CoV-2 vaccine severe acute respiratory syndrome Coronavirus similarity Sinopharm Sinovac storage the vaccine Transport trials Vaccine vaccine candidate vaccine platform Vaccines virion virus particle WHO World Health Organization worldwide pandemic Wuhan [DOI] 10.1002/jcla.24418 PMC 바로가기 [Article Type] Review
Conserved Pattern and Potential Role of Recurrent Deletions in SARS-CoV-2 EvolutionSARS-CoV-2 진화에서 보존된 패턴 및 반복 삭제의 잠재적 역할Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] adaptive adaptive evolution addition association binding site Combination coronavirus COVID-19 deleted Deletion deletions described disease distribution Epidemic Evidence Evolution functions genome structure greater Host human host indicated insertion insertions integration means Mutation N-terminal domain Neutralizing antibodies NSP6 nucleotide nucleotide change occurred pattern Potential Prevention and control Previous studies proliferation Protein RDRs Receptor binding domain Recurrent recurrent deletion Region regions reported role SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes SARS-related coronavirus SARS-related coronaviruses single nucleotide Spike protein Strains Structural variation structural variation. structural variations the spike protein the WHO unique Vaccine development variant variants variants of concern variants of interest Variation Viral viral genome virus Virus evolution viruses VoC whole genome worldwide pandemic Δ144 Δ69-70 [DOI] 10.1128/spectrum.02191-21 PMC 바로가기 [Article Type] Article
Machine Learning, Deep Learning, and Mathematical Models to Analyze Forecasting and Epidemiology of COVID-19: A Systematic Literature ReviewCOVID-19의 예측 및 역학 분석을 위한 머신 러닝, 딥 러닝 및 수학적 모델: 체계적인 문헌 검토Review Published on 2022-04-222022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 치료기술, [키워드] agency Algorithm Algorithms article automatic detection basic reproduction rate battle caused classification CNN compartmental model COVID-19 criteria current deep deep learning disease Epidemic epidemiological Epidemiology epidemiology of COVID-19 estimate feature first stage Forecasting generate Health Organization healthcare Healthcare industry healthy highlight item Laboratory learning life literature machine learning mathematical Mathematical models medical staff meta-analyses Model PRISMA PROTECT recorded reduce Reporting Reproduction rate Research researcher review SARS-CoV-2 selected shown Spread spread of COVID-19 SVM systematic reviews the epidemic World Health Organization worldwide pandemic Wuhan Wuhan, China [DOI] 10.3390/ijerph19095099 PMC 바로가기 [Article Type] Review
The SARS-CoV-2 spike residues 616/644 and 1138/1169 delineate two antibody epitopes in COVID-19 mRNA COMINARTY vaccine (Pfizer/BioNTech)SARS-CoV-2 스파이크 잔기 616/644 및 1138/1169는 COVID-19 mRNA COMINARTY 백신에서 2개의 항체 에피토프를 나타냅니다(화이자/바이오엔텍)Article Published on 2022-04-092022-09-12 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] antibody epitope Antibody Response Antigen B-cell epitope BALB/c mice conjugate contribute coronavirus SARS-CoV-2 COVID-19 COVID-19 mRNA vaccines COVID-19 recovered patients COVID-19 vaccine COVID-19 vaccines effective Efficacy effort ELISA assay full-length identify immune immunogenic individuals linear B-cell epitope mRNA peptide peptide-based performed Pfizer-BioNTech Pfizer/BioNTech Protective question raise recipient residue responsible SARS-CoV-2 spike SARS-CoV-2 spike protein sera the SARS-CoV-2 the spike protein Vaccine worldwide pandemic [DOI] 10.1038/s41598-022-10057-7 PMC 바로가기 [Article Type] Article
A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques캡시드 바이러스 유사 입자 기반 SARS-CoV-2 백신은 높은 수준의 항체를 유도하고 붉은털 원숭이를 보호합니다Article Published on 2022-04-052022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Antibody titers binding binding and neutralizing antibodies broad neutralizing antibodies capsid caused clinical testing comparable control group convalescent Corona coronavirus COVID-19 demonstrated disease dose-dependent manner Efficacy Evidence evidence of immunogenicity increase in Level macaque mice Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers no evidence of non-human primate non-human primates non-human primates (NHP) protection Protective reduction in respiratory rhesus macaques SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 single vaccination Vaccine vaccine administration vaccine group variants variants of concern variants of concern (VOCs) Viral Viral load Virus-like particle virus-like particles virus-like particles (VLP). VLP VOCs worldwide pandemic [DOI] 10.3389/fimmu.2022.857440 PMC 바로가기 [Article Type] Article
Genetic association of IL17 and the importance of ABO blood group antigens in saliva to COVID-19IL17의 유전적 연관성과 코로나19에 대한 타액 내 ABO 혈액형 항원의 중요성Article Published on 2022-03-092022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, 치료기술, [키워드] ABO Activation Analysis Antigen association Blood Group carried caused conducted COVID-19 COVID-19 patient determine Factor FOXP4 FOXP4-AS1 FUT2 General population Genetic genetic association genetic factors genetics genome-wide association Genome-wide association study Genomic analysis Genotype GWAS identify IFNAR2 IL17 IL17A IL17F individual infection with SARS-CoV-2 innate immune response International involved Japan Japanese Meta-analysis mRNA expression nine outbreak Patient presenting replicated reported Respiratory failure risk allele Risk factors Saliva SARS-COV-2 infection SARS-CoV-2 virus severe COVID-19 severity severity of COVID-19 significantly significantly lower SNP virus worldwide pandemic [DOI] 10.1038/s41598-022-07856-3 PMC 바로가기 [Article Type] Article
Central nervous system outcomes of COVID-19Review article Published on 2022-03-012022-10-05 Journal: Translational research : the journal of laboratory [Category] SARS, 바이오마커, [키워드] ACE2angiotensin converting enzyme 2 acute illness acute respiratory distress syndrome acute respiratory syndrome angiotensin converting enzyme 2 approach ARDSacute respiratory distress syndrome caused Central nervous system cerebral spinal fluid CFScerebral spinal fluid Chitinase 3-like 1. CNSCentral Nervous System coronavirus COVID-19 Critical deaths example GBSGuillain-Barré syndrome GFAPGlial Fibrillary Acidic Protein Glial fibrillary acidic protein Guillain-barrè syndrome identify Implications Loss of Smell manifestation ME/CFSmyalgic encephalomyelitis/chronic fatigue syndrome Mild Myalgic encephalomyelitis/chronic fatigue syndrome nervous system neurofilament light chain neurologic neurological Neurological symptom NfLneurofilament light chain outcome PASC PASCpostacute sequelae of COVID-19 pathophysiology PCRpolymerase chain reaction Peripheral nervous system PNSPeripheral nervous system polymerase chain reaction postacute sequelae of COVID-19 reported Research Respiratory disease SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2severe acute respiratory syndrome coronavirus 2 Seizure severe acute respiratory syndrome coronavirus 2 stroke Symptom the disease the SARS-CoV-2 virus these symptom these symptoms ubiquitin carboxyl-terminal esterase L1 UCH-L1ubiquitin carboxyl-terminal esterase L1 worldwide pandemic YKL-40Chitinase 3-like 1. [DOI] 10.1016/j.trsl.2021.09.002 [Article Type] Review article
Powerful CRISPR-Based Biosensing Techniques and Their Integration With Microfluidic PlatformsBioengineering and Biotechnology Published on 2022-02-232022-10-31 Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19, [키워드] amplification Analysis biosensor Combination coronavirus disease costly COVID-19 CRISPR CRISPR/Cas systems Cycling Efficiency equipment healthcare integration isothermal amplification limitation microfluidic techniques New Nucleic acid detection outlined palindromic repeat PCR performed physiological temperature point-of-care powerful tool provide reducing Sensitivity and specificity specificity technique worldwide pandemic [DOI] 10.3389/fbioe.2022.851712 PMC 바로가기 [Article Type] Bioengineering and Biotechnology
Dihydroartemisinin attenuates pulmonary inflammation and fibrosis in rats by suppressing JAK2/STAT3 signalingResearch Paper Published on 2022-02-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, [키워드] activated Activation alveolar inflammation analyzed attenuate cause caused CCL3 change chemokine collagen Coronavirus disease 2019 COVID-19 dihydroartemisinin effective expression fibrosis growth hydroxyproline IL-6 Inflammatory response inhibit inhibited inhibiting inhibitory effect JAK2 JAK2/STAT3 JAK2/STAT3 signaling janus lung Lung injury lung tissue molecular analysis molecular mechanism Necrosis phosphorylated pulmonary fibrosis pulmonary inflammation reduced representing SARS-CoV-2 serum Signaling staining STAT3 TGF-β1 therapeutic therapeutic effect TNFα treat Treatment with COVID-19 worldwide pandemic [DOI] 10.18632/aging.203874 PMC 바로가기 [Article Type] Research Paper