Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational studyObservational Study Published on 2021-01-142022-10-04 Journal: BMC Infectious Diseases [Category] 임상, [키워드] 95% CI Analysis arrhythmia association associations Cohort COVID-19 diagnosed effective Electronic health record event examined Hospitalization Hospitalized hospitalized COVID-19 patient Hydroxychloroquine hydroxychloroquine therapy Logistic majority mildly symptomatic patient multivariable multivariable logistic regression New observational study occurred outcome Outpatient Patient Primary outcome progression of disease Prophylaxis QTC prolongation randomized trial reported Result retrospective SARS-CoV-2 SARS-COV-2 infection subsequent supplementary material survival symptomatic Treatment USA was obtained [DOI] 10.1186/s12879-021-05773-w PMC 바로가기 [Article Type] Observational Study
Increased Fecal Neopterin Parallels Gastrointestinal Symptoms in COVID-19Article Published on 2021-01-122022-10-31 Journal: Clinical and Translational Gastroenterology [Category] COVID-19, MERS, [키워드] COVID-19 COVID-19 patient disease driven by elevated exhibited fecal Gastrointestinal Gastrointestinal symptom gastrointestinal symptoms gastrointestinal tract healthy controls hospitalized COVID-19 patient Increased Inflammation inflammatory immune response intensive care interferon-γ Macrophage marker measure Most patient Patient respiratory symptom Spread Stool worldwide pandemic Wuhan, China [DOI] 10.14309/ctg.0000000000000293 PMC 바로가기 [Article Type] Article
Low ADAMTS13 Activity Correlates with Increased Mortality in COVID-19 PatientsOriginal Article Published on 2021-01-092022-10-29 Journal: TH Open: Companion Journal to Thrombosis and Haemostasis [Category] COVID-19, [키워드] Activation activity ADAMTS13 Admission Antigen association Biomarker Biomarkers cause Coagulation Coagulopathy conducted coronavirus disease COVID-19 COVID-19 patient D-dimer died discharged disease severity distribution Efficacy elevated elevated lactate dehydrogenase endothelial greater Hemolysis hospitalized COVID-19 patient hospitalized patients Increased less metalloproteinase Mortality motif nonsurvivors organ damage Patient Presence Randomly Retrospective study schistocytes selected significantly significantly increased significantly lower subset survived survivor Treatment von Willebrand factor vWF [DOI] 10.1055/s-0041-1723784 PMC 바로가기 [Article Type] Original Article
SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotypeSARS-CoV-2 감염은 전혈전성 혈소판 표현형과 관련이 있습니다Article Published on 2021-01-052022-09-11 Journal: Cell Death & Disease [Category] 치료기술, [키워드] abnormal coagulation Activation addition Adhesion Molecule adhesion molecules antibodies antiplatelet Antithrombotic cardiovascular complications CD63 characterized Coagulation complex condition contribute Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients COVID-19 sample COVID-19 samples Cytometry donors expressed expression healthy control healthy controls hospitalized COVID-19 patient hospitalized COVID-19 patients hypercoagulable Hypercoagulable state in vitro incidence intensity intensive care intensive care support interactions investigated involved LAMP marker mass Mechanisms of disease median novel Novel coronavirus novel coronavirus disease P-selectin parameter patients peptide phenotype phenotypical Platelet platelet activation Platelets pro-thrombotic reduced Research SARS-COV-2 infection selectin signal intensity significantly Stimulation Support thrombin thrombin receptor transmembrane protein TRAP Treatment viral infection [DOI] 10.1038/s41419-020-03333-9 PMC 바로가기 [Article Type] Article
Associations Between Genetically Predicted Protein Levels and COVID-19 SeverityArticle Published on 2021-01-042022-10-04 Journal: The Journal of Infectious Diseases [Category] 신약개발, [키워드] association associations Bonferroni correction controls COVID-19 COVID-19 severity Critical false discovery rate Genetic genetic instruments hospitalized COVID-19 patient identify initiative Level positive predicted Protein protein level Proteins SARS-CoV-2 severity target with COVID-19 [DOI] 10.1093/infdis/jiaa660 PMC 바로가기 [Article Type] Article
Association of liver steatosis and fibrosis with clinical outcomes in patients with SARS-CoV-2 infection (COVID-19)SARS-CoV-2 감염(COVID-19) 환자의 임상 결과와 간 지방증 및 섬유증의 연관성Article Published on 2021-01-012022-09-11 Journal: Annals of hepatology [Category] SARS, 바이오마커, [키워드] abnormality Admission association clinical Clinical outcome clinical outcomes Comorbidity conducted COVID-19 COVID-19 patient COVID-19 patients determine FIB-4 fibrosis hospitalized COVID-19 patient hospitalized COVID-19 patients ICU ICU admission independent Infection intensive care unit liver Liver fibrosis Liver function test liver function tests liver steatosis male material Mortality NAFLD obese outcome outcomes patients patients with COVID-19 patients with SARS-CoV-2 Prevalence reported Retrospective study risk SARS-CoV-2 steatosis [DOI] 10.1016/j.aohep.2020.09.015 PMC 바로가기 [Article Type] Article
High Prevalence of Gastrointestinal Manifestations of COVID-19 Infection in Hospitalized Patients With CancerObservational Study Published on 2021-01-012022-10-05 Journal: Journal of clinical gastroenterology [Category] 임상, [키워드] active malignancy anorexia Cancer cancer patient Cancer patients Coronavirus disease-19 COVID-19 diarrhea elevated Elevation evaluated Fever Gastrointestinal GI symptom had no Hospitalized hospitalized COVID-19 patient hospitalized patient initial symptom liver transaminase manifestation Massachusett material multicenter cohort study occur oncology patients Patient patients patients hospitalized Patients with cancer performed predominant presenting Prevalence prevalent reported respiratory symptoms SARS-COV-2 infection severity subset Symptom transaminase vomiting with COVID-19 [DOI] 10.1097/MCG.0000000000001462 PMC 바로가기 [Article Type] Observational Study
Acute kidney failure in patients admitted due to COVID-19Observational Study Published on 2021-01-012022-10-05 Journal: Nefrología [Category] SARS, 임상, [키워드] Acute kidney injury acute respiratory distress acute tubular necrosis age AKI analyzed baseline characteristics biological drug C-reactive protein cardiological caused Chronic kidney disease clinical evolution collected complications Coronavirus 2019 COVID-19 COVID-19 case COVID-19 patients D-dimer values develop died Enfermedad renal etiology Fluid management Fracaso renal agudo global pandemic glomerular hematological Hematuria hospital Hospital stay Hospitalization hospitalized COVID-19 patient Hypovolemia ICU admission intensive care IQR kidney Kidney disease Kidney injury LDH males management mechanism Nephrology Neumonía outbreak Patient patients Pneumonia Prognostic factor Prospective Study pulmonary damage renal renal damage renal replacement therapy reported required respiratory infection SARS-CoV-2 Sepsis severe pneumonia Spain syndrome took place Toxicity Tratamiento renal sustitutivo. Treatment World Health Organization Wuhan, China [DOI] 10.1016/j.nefro.2020.08.005 PMC 바로가기 [Article Type] Observational Study
A retrospective study on the prevalence of anti-phospholipid antibodies, thrombotic events and cutaneous signs of vasculopathy in 173 hospitalized COVID-19 patients입원한 코로나19 환자 173명을 대상으로 한 항인지질항체 유병률, 혈전성 질환, 혈관병증 피부 징후에 대한 후향적 연구Article Published on 2021-01-012022-09-12 Journal: International journal of immunopathology and pharm [Category] MERS, 진단, [키워드] acrocyanosis adjusted affecting analyzed Anti-phospholipid antibodies anti-phospholipid syndrome antibodies antibody Artery association COVID-19 COVID-19 patients COVID-19 severity cutaneous manifestation enrolled event events hospitalized COVID-19 patient hypercoagulability Hypercoagulation involved Ischemia livedo reticularis manifestation Mortality nine not correlated occurred Patient patients patients with COVID-19 Prevalence pulmonary embolisms responsible Retrospective study risk factor SARS-CoV-2 serum sample syndrome the patient Thromboembolic event Thromboembolic events thrombosis thrombotic event Typical Vascular Vasculopathy [DOI] 10.1177/20587384211042115 PMC 바로가기 [Article Type] Article
A Retrospective Look at Recent COVID-19 Articles Published in Cell Transplantation: Research Leading to Further Understanding세포 이식에 게재된 최근 COVID-19 기사에 대한 회고적 검토: 더 많은 이해를 이끄는 연구Article Published on 2021-01-012022-09-11 Journal: Cell transplantation [Category] 변종, [키워드] ACE2 acute respiratory diseases androgen Androgen receptors angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 article cell transplantation cellular cellular therapy Characteristics consequence COVID-19 COVID-19 pandemic COVID-19 severity Cytokines disease disease severity enzyme Genes group Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients immune infused Intervention leading mesenchymal stem cell Mesenchymal stem cells modulating MSC offered pandemic Perspective principle proof recent receptor reduced Research respiratory diseases SARS-CoV2 Serine stem cells supported the disease therapy TMPRSS2 transmembrane serine protease transplantation Treatment understanding unique Variability variant variants [DOI] 10.1177/09636897211049814 PMC 바로가기 [Article Type] Article