Obstetric outcomes in pregnant COVID-19 women: the imbalance of von Willebrand factor and ADAMTS13 axis임신 한 Covid-19 여성의 산과 적 결과 : Von Willebrand Factor and Adamts13 축의 불균형Observational Study Published on 2022-02-212022-09-10 Journal: BMC Pregnancy and Childbirth [Category] COVID19(2023년), Fulltext, MERS, SARS, 바이오마커, 유전자 메커니즘, 임상, [키워드] 95%CI AB0 blood group system ADA ADAMTS13 Admission adverse outcomes age association Asymptomatic Biomarker clinical information clinical outcomes collected confounders COVID-19 COVID-19 patient COVID-19 patients damage Decision making decision making process demographic diagnosis of SARS-CoV-2 discharge evaluate Follow-up gestational age hospital Hospital admission Imbalance independent Infection investigated Italy laboratory data laboratory parameter Laboratory parameters laboratory-confirmed Logistic regression Logistic regression analysis marker mechanism median microangiopathy monitoring outcome Pregnancy pregnant pregnant women preterm delivery regression analysis responsible Result risk SARS-COV-2 infection significantly significantly higher significantly lower Support Symptom symptom of infection thrombotic microangiopathy von Willebrand factor was performed with COVID-19 [DOI] 10.1186/s12884-022-04405-8 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2-related mortality and treatment delays for cancer patients in Austria Findings of a multicentric nationwide studyOriginal Article Published on 2022-02-162022-10-29 Journal: Wiener Klinische Wochenschrift [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] acute respiratory syndrome adverse outcomes albumin level association cancer patient cancer treatment Cohort cohort study collected comparable coronavirus coronavirus disease COVID-19 COVID-19 diagnosis diagnosed Diagnosis died disease Factor finding Follow-up General population Hematologic malignancy Hospital admission increased risk independent risk factor investigated Lymphocyte count malignant disease Mortality neutrophil count Older outcome pandemic parameter Patient patients performance status Predictive quarantine Result risk factor Risk factors SARS-CoV-2 SARS-CoV‑2 SARS-CoV‑2 infection SARS-CoV‑2 infection solid tumors Survivors therapy treated Treatment [DOI] 10.1007/s00508-022-02006-1 PMC 바로가기 [Article Type] Original Article
Mortality and readmission rates among hospitalized COVID-19 patients with varying stages of chronic kidney disease: a multicenter retrospective cohortObservational Study Published on 2022-02-102022-10-04 Journal: Scientific Reports [Category] MERS, 임상, 치료법, [키워드] Admission adverse outcomes chronic Chronic kidney disease CKD clinician Cohort coronavirus disease COVID-19 COVID-19 patient death determine hospitalized COVID-19 patient hospitalized patient Infection Infectious diseases kidney Kidney disease kidney transplant Mortality multicenter multicenter cohort study Observational cohort study Odds ratio outcome Patient patients patients hospitalized PCR-confirmed performed prevalent ranged readmission retrospective cohort risk factor SARS-COV-2 infection severe COVID-19 severity Stage stages [DOI] 10.1038/s41598-022-06276-7 PMC 바로가기 [Article Type] Observational Study
COVID-19 vaccine acceptability among people in Australia who inject drugs: Implications for vaccine rollout약물을 주사하는 호주 사람들의 Covid-19 백신 수용 가능성 : 백신 롤아웃에 대한 시사점Article Published on 2022-02-012022-08-31 Journal: Drug and alcohol review [Category] COVID19(2023년), MERS, SARS, 치료제, [키워드] adverse outcome adverse outcomes Characteristics COVID-19 COVID-19 vaccine COVID-19 vaccines cross-sectional study disease distribution drug drug treatment effort Hesitancy hypothetical hypothetical vaccine acceptability indicated injected majority Melbourne Melbourne, Australia mouth Older participant People who inject drugs reason reason for recruited reduce reported risk Treatment vaccination Vaccine Vaccine hesitancy [DOI] 10.1111/dar.13399 PMC 바로가기 [Article Type] Article
Lymphopenia as a Predictor for Adverse Clinical Outcomes in Hospitalized Patients with COVID-19: A Single Center Retrospective Study of 4485 CasesArticle Published on 2022-01-282022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval Absolute lymphocyte count Admission Adverse adverse clinical outcomes adverse outcome adverse outcomes age center characteristic clinical clinical outcomes Comorbidities COVID-19 cubic spline determine dialysis expressed Gender hospital hospitalized COVID-19 patients ICU admission in-hospital mortality incidence increase in Invasive mechanical ventilation laboratory-confirmed Lymphocyte count lymphopenia Non-linear relationship Odds ratio outcome outcomes Patient patients with COVID-19 predict predictive power receiver operating characteristic curves restricted cubic splines retrospective risk was performed [DOI] 10.3390/jcm11030700 PMC 바로가기 [Article Type] Article
The Efficacy and Safety of Janus Kinase Inhibitors for Patients With COVID-19: A Living Systematic Review and Meta-AnalysisMedicine Published on 2022-01-272022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI adverse events adverse outcomes Analysis Baricitinib baseline Clinical outcome contribute COVID-19 database decrease decreased mortality demonstrated Efficacy and safety eligible evaluated Evidence Hospitalized hospitalized patient incidence increased mortality JAK inhibitor jak inhibitors janus Janus kinase Janus kinase inhibitors kinase Meta-analysis Mortality no increase observational study outcome Patient patients with COVID-19 Randomized controlled trial RCTs Registration required Result retrieved review risk ruxolitinib Safety SARS-CoV-2 searched significant decrease significantly subgroup analysis supplemental oxygen systematic review the cytokine storm Tofacitinib Treatment Ventilation with COVID-19 [DOI] 10.3389/fmed.2021.800492 PMC 바로가기 [Article Type] Medicine
Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African CountriesResearch Published on 2022-01-192022-10-31 Journal: JAMA Pediatrics [Category] COVID-19, MERS, SARS, [키워드] 95% CI adjusted adjusted odds ratio Admission Adolescent adverse outcomes African age assessment children clinical Clinical outcome Clinical practice cohort study Comorbidities Comorbidity country COVID-19 COVID-19 vaccination death died discharged disease disorder exposure expressed Factor finding hazard ratio Health hematological high risk hospital hospital discharge Hospital stay Hospitalization Hospitalized hospitalized patient hypertension ICU admission implication Importance Infant Inflammatory intensive care Invasive mechanical ventilation IQR Kenya likelihood Lung disease male measure morbidity and mortality Nigeria objective outcome outcomes oxygen supplementation participant Patient patients pediatric Point Population preexisting comorbidities preexisting comorbidity prevalent Primary outcome reduced Relevance remained reported required Result retrospective SARS-COV-2 infection secondary outcome setting severity Sex South Africa sub-Saharan Africa subdistribution syndrome the median therapeutic intervention Uganda was used with COVID-19 [DOI] 10.1001/jamapediatrics.2021.6436 PMC 바로가기 [Article Type] Research
Perspectives on frailty screening, management and its implementation among acute care providers in Singapore: a qualitative studyResearch Published on 2022-01-172022-10-27 Journal: BMC Geriatrics [Category] Coronavirus, SARS, [키워드] Accident adverse outcomes Analysis Anesthesia approach Care clinician Cluster concerning Consensus COVID-19 pandemic develop Emergency facilitator Follow-up frailty Frailty Screening group discussion healthcare healthcare providers high risk hospital hospitals identify implementation IMPROVE indicated management Nurse Older older patient Orthopedics participant Patient patients Perspective physical physician populations professional Prognosis proportion provided public health Purposive sampling recruited resources Result Screening Singapore Specific supplementary material Support surgery Treatment was performed [DOI] 10.1186/s12877-021-02686-w PMC 바로가기 [Article Type] Research
Clinical Characteristics, Outcomes, and Risk Factors of Disease Severity in Patients With COVID-19 and With a History of Cerebrovascular Disease in Wuhan, China: A Retrospective StudyNeurology Published on 2022-01-112022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] 95% CI acute respiratory syndrome Admission adverse outcome adverse outcomes age albumin analyses Analysis analyzed Blood urea nitrogen C-reactive protein cerebrovascular Cerebrovascular disease chronic obstructive clinical Clinical characteristics clinical feature Clinical outcome clinical study Comorbidities confirmed case confounding effect consecutive patient Coronary heart disease coronavirus Coronavirus disease 2019 COVID-19 CVD death Decreased diabetes difference event Factor higher risk history Hospitalization Huoshenshan Hospital hypertension incidence intensive care investigated lactate dehydrogenase lymphocyte Lymphocyte count mechanical ventilation multivariate logistic regression neutrophil Odds ratio Older pandemic Patient patients with COVID-19 propensity score matching pulmonary disease retrospective risk factor Risk factors Sex Shock single-center smoking two group White blood cell Wuhan [DOI] 10.3389/fneur.2021.706478 PMC 바로가기 [Article Type] Neurology
The Potential Mechanism of Cancer Patients Appearing More Vulnerable to SARS-CoV-2 and Poor Outcomes: A Pan-Cancer Bioinformatics AnalysisSARS-CoV-2에 더 취약하고 좋지 않은 결과를 보이는 암 환자의 잠재적 기전: 범암 생물정보학 분석Immunology Published on 2022-01-102022-09-11 Journal: Frontiers in Immunology [Category] MERS, 변종, 유전자 메커니즘, [키워드] ACE2 ACE2 expression adverse outcome adverse outcomes Affect Bioinformatics analysis Cancer cancer patient Cancer patients conducted correlated COVID-19 COVID-19 severity drugs dysregulation Factor Genes Genetic genetic factors Genotype healthy subjects higher risk Host host gene host genes immune infiltration immune response immune responses individual infected with SARS-CoV-2 infiltration inhibit Intervention lower expression negative influence NPC1 OAS1 outcome outcomes overall survival Patient Poor Potential potential mechanism protective factor rs10774671 (OAS1) SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility sensitivity survival target Treatment variant variants [DOI] 10.3389/fimmu.2021.804387 PMC 바로가기 [Article Type] Immunology