protein synthesis – Page 4 – Communicable Diseases Research

MicroRNAs and SARS-CoV-2 life cycle, pathogenesis, and mutations: biomarkers or therapeutic agents?

MicroRNA와 SARS-CoV-2 수명 주기, 병인 및 돌연변이: 바이오마커 또는 치료제?

Review

Published on 2021-01-012022-09-11
Journal: Cell cycle (Georgetown, Tex.) [Category] MERS, SARS, 바이오마커, 변종, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral antiviral agent antiviral drug antiviral drugs applied binding Biomarker candidate cell proliferation complementary coronavirus coronavirus disease Coronavirus disease 2019 coronavirus vaccine COVID-19 COVID-19 therapy database databases determine differentiation drug Drug administration Efficacy Emergency use authorization food genomic genomic mutations Google Scholar involved life cycle metabolism microRNA miRNA miRNAs mRNA degradation mutations Pathogenesis pathological conditions pathophysiology patients patogenecity physiological protein synthesis respiratory RNAs SARS-CoV-2 SARS-CoV-2 life cycle searched severe acute respiratory syndrome Coronavirus shown single-stranded Stage target mRNA the SARS-CoV-2 the United State therapeutic therapy United States United States Food and Drug Administration untranslated region UTR Vaccine virus Web of Science
[DOI] 10.1080/15384101.2020.1867792 PMC 바로가기 [Article Type] Review

Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

SARS-CoV-2의 비구조 단백질 1은 숙주 단백질 합성 기계를 바이러스 RNA로 리디렉션하는 강력한 병원성 인자입니다

Article

Published on 2020-12-172022-09-11
Journal: Molecular Cell [Category] MERS, SARS, 유전자 메커니즘, 진단,

Rhodanine derivative LJ001 inhibits TGEV and PDCoV replication in vitro

Article

Published on 2020-09-192022-11-01
Journal: Virus research [Category] Coronavirus,

Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction

Cell and Developmental Biology

Published on 2020-08-262022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

SARS-CoV-2 Codon Usage Bias Downregulates Host Expressed Genes With Similar Codon Usage

Cell and Developmental Biology

Published on 2020-08-202022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

Subcutaneous administration of interferon beta-1a for COVID-19: A non-controlled prospective trial

Article

Published on 2020-06-072022-10-04
Journal: International immunopharmacology [Category] MERS, SARS, 임상,

[키워드] administration Adverse drug reaction age Antiviral clearance clinical Clinical symptoms Combination coronavirus country COVID-19 death demographic dose Effect Epidemic evaluate Hospitalization Hydroxychloroquine imaging immunomodulatory effects include infected cells interferon Interferon beta-1a interferons management maturation New coronavirus Patient patients previous study Prospective trial protein synthesis Pulmonary infection recorded resolved Result Seven shown significant decrease Spread subcutaneous administration subcutaneously Support susceptible Symptom the patient therapeutic effect therapy Trial Trial registration viral replication virological clearance virus
[DOI] 10.1016/j.intimp.2020.106688 PMC 바로가기 [Article Type] Article

COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

Research Perspective

Published on 2020-04-302022-10-28
Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS,

[키워드] ACE-2 age aging angiotensin-converting enzyme 2 antibiotic Antibiotics association Azithromycin Beta-galactosidase CD26 cellular China clinical trial Compound Corona virus COVID-19 COVID-19 disease COVID-19 infection disease doxycycline drug Drug repurposing FDA-approved drugs functional host receptor Hydroxy-chloroquine Hypothesis IL-6 inhibit inhibitor marker MERS Middle East mortality rate Other pandemic Patient preventing the transmission prevention prevention of COVID-19 profiles protein synthesis quercetin question Rapamycin respiratory resulting SARS-CoV-2 SASP senescence senolytic drug therapy Side-effect Spread Treatment viral replication virus zoonotic
[DOI] 10.18632/aging.103001 PMC 바로가기 [Article Type] Research Perspective

The Porcine Deltacoronavirus Replication Organelle Comprises Double-Membrane Vesicles and Zippered Endoplasmic Reticulum with Double-Membrane Spherules

Article

Published on 2019-11-052022-10-28
Journal: Viruses [Category] Coronavirus,

UBXN1 interacts with the S1 protein of transmissible gastroenteritis coronavirus and plays a role in viral replication

Research Article

Published on 2019-04-272022-10-28
Journal: Veterinary Research [Category] Coronavirus,

[키워드] Antiviral binding cause cDNA library Cell cells clone coronavirus Degradation diarrhea downregulated expression expression level gastroenteritis glycoprotein GST host receptor identify IFN-β in viral indicated Infection inhibition interact intestinal cell intracellular protein involved late phase morbidity and mortality negative control overexpression positive Protein protein domain protein synthesis provided regulate Replication Research responsible Sequencing sialic acid Signal transduction signaling pathways significantly significantly increased siRNA TGEV the S1 protein UBXN1 viral titer yeast
[DOI] 10.1186/s13567-019-0648-9 PMC 바로가기 [Article Type] Research Article

Pneumococcal RNase R globally impacts protein synthesis by regulating the amount of actively translating ribosomes

article

Published on 2019-02-282024-09-01
Journal: RNA Biology [Category] 폐렴구균 감염증,

[키워드] 70S EF-G IF3 protein synthesis ribosome ribosome dissociation RNase RRF translation
[Article Type] article