A reduced graphene oxide-Fe 3 O 4 composite functionalized with cetyltrimethylammonium bromide for efficient adsorption of SARS-CoV-2 spike pseudovirus and human enteric virusesSARS-CoV-2 스파이크 슈도바이러스 및 인간 장내 바이러스의 효율적인 흡착을 위해 세틸트리메틸암모늄 브로마이드로 기능화된 환원그래핀옥사이드-Fe 3 O 4 복합체Article Published on 2022-03-012022-09-11 Journal: Chemosphere [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Adsorption cetyltrimethylammonium bromide Combination complex Composite coronavirus CTAB Detection limit electrostatic interaction electrostatic interactions exhibited Fourier-transform infrared spectroscopy Genome HRV Human Human enteric viruses infrared spectroscopy intrinsic pseudovirus public health qPCR analysis reduced Reduced graphene oxide SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike pseudovirus severe acute respiratory syndrome Coronavirus significantly tap transmission electron microscopy Viral transmission virion Virion adsorption. virions virus virus particle virus particles water X-ray diffraction zeta potential [DOI] 10.1016/j.chemosphere.2021.132995 PMC 바로가기 [Article Type] Article
Case Report: Hypergranular Platelets in Vaccine-Induced Thrombotic Thrombocytopenia After ChAdOx1 nCov-19 VaccinationCardiovascular Medicine Published on 2022-02-092022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] Admission antibody anticoagulation treatment approach ATP ChAdOx1 ChAdOx1 nCov-19 vaccination characterized contribute D-dimer female Granule healthy healthy control help hematological parameter highlight hospital investigated marker morphology observation parameter pathology Patient Peripheral blood peripheral blood smear Platelet Platelets Population presentation reduced remained returned SARS-CoV-2 vaccination study period TEM the patient therapeutic decision thrombocytopenia thrombosis thrombotic thrombotic risk transmission electron microscopy Treatment vaccination vaccine-induced thrombotic thrombocytopenia (VITT) venous was increased were assessed [DOI] 10.3389/fcvm.2022.824601 PMC 바로가기 [Article Type] Cardiovascular Medicine
Effects of Different Drug Therapies and COVID-19 mRNA Vaccination on Semen Quality in a Man with Ankylosing Spondylitis: A Case ReportCase Report Published on 2022-01-242022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] Abnormalities adverse effect Affect analysed Analysis ankylosing spondylitis Case report Celecoxib Cell Characteristics Concentration COVID-19 DNA fragmentation dose drug Effect evaluated examined flow cytometry Golimumab had no healthy incidence Inflammation light microscopy limit Man material morphology mRNA mRNA COVID-19 vaccine mRNA vaccination mRNA vaccine parameter phagocyte Pregnancy Quality reduced remained report Semen Sperm sulphasalazine TEM the patient therapy transmission electron microscopy transmission electron microscopy (TEM) Treatment vaccination white cell [DOI] 10.3390/medicina58020173 PMC 바로가기 [Article Type] Case Report
SARS-CoV-2: Ultrastructural Characterization of Morphogenesis in an In Vitro SystemArticle Published on 2022-01-202022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] 3D electron microscopy modeling acute respiratory syndrome antiviral drugs caused Cell cell membrane cellular compartments change characterization conducted coronavirus cytoplasmic membrane described Endoplasmic reticulum Exocytosis impacted in vitro lipid droplet MERS-CoV Microscopy morphogenesis occurred pandemic Particle performed progeny proliferation Prophylactic public health Replication replication mechanism SARS-CoV SARS-CoV-2 SARS-COV-2 infection scanning electron microscopy susceptible syncytia formation System therapeutic took place Transmission transmission electron microscopy ultrastructural studies understanding Vero-E6 cell Vero-E6 cells Vesicle virus [DOI] 10.3390/v14020201 PMC 바로가기 [Article Type] Article
The atomic portrait of SARS‐CoV‐2 as captured by cryo‐electron microscopy극저온 전자 현미경으로 포착한 SARS-CoV-2의 원자 초상화Review Published on 2021-12-142022-09-12 Journal: Journal of Cellular and Molecular Medicine [Category] Coronavirus, SARS, 진단, [키워드] antibodies Antibody binding atomic atomic level COVID‐19 cryo‐electron microscopy cryo‐electron tomography death drug economic devastation globe host cell Interaction Microscopy offer Research SARS‐CoV‐2 SARS‐CoV‐2 proteins SARS‐CoV‐2 single‐particle analysis spike Spread structural biology transmission electron microscopy unique virus [DOI] 10.1111/jcmm.17103 PMC 바로가기 [Article Type] Review
Voltammetric sensor based on bimetallic nanocomposite for determination of favipiravir as an antiviral drug항바이러스 약물로서의 파비피라비르 측정을 위한 바이메탈 나노복합체 기반 전압전류 센서Article Published on 2021-11-272022-09-11 Journal: Mikrochimica Acta [Category] 치료제, [키워드] active site active sites AgCl Amino acid amino acids antiviral drug antiviral drugs Biological Biological sample analysis carbon Carbon nanotube clinical samples compounds condition Conductive polymer COVID-19 demonstrated diagnosing electron microscopy Favipiravir human plasma sample human plasma samples limit of detection linear Microscopy multi Polymer polystyrene sulfonate quantitative range repeatability reproducibility scanning electron microscopy SEM silver stability Standard deviation sulfonate surface area TEM transmission electron microscopy ultraviolet Urine voltammetry X-ray diffraction X-ray spectroscopy [DOI] 10.1007/s00604-021-05107-2 PMC 바로가기 [Article Type] Article
Physicochemical Characteristics and In Vitro Toxicity/Anti-SARS-CoV-2 Activity of Favipiravir Solid Lipid Nanoparticles (SLNs)Article Published on 2021-10-192022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] ACI activity acute respiratory syndrome Anti-viral anti-viral activity coronavirus Coronavirus infection COVID-19 defined develop disease Efficacy evaluated Favipiravir Fourier-transform infrared spectroscopy FPV fraction IC50 in vitro Infection inhalation Inhaled Lipid Local Lungs morphology nanoparticle nebulizer pathogen physicochemical produced SARS-CoV-2 scattering Solid solid lipid nanoparticle the SARS-CoV-2 transmission electron microscopy treat [DOI] 10.3390/ph14101059 PMC 바로가기 [Article Type] Article
Liver Histopathological Analysis of 24 Postmortem Findings of Patients With COVID-19 in ChinaMedicine Published on 2021-10-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] change changes in China cholestasis coronavirus COVID-19 COVID-19 case COVID-19 patient COVID-19 patients edematous edematous of mitochondria Endoplasmic reticulum expansions of endoplasmic reticulum finding had more hepatocellular hepatocytes Inclusion independent Infection Inflammation LIGHT liver liver histopathological analysis Liver injury liver tissue lobular inflammation male manifested Microscopy Necrosis Obstructive Particle pathologic Patient Postmortem Respiratory failure Sample SARS-CoV-2 Schistosoma sinusoids steatosis susceptible transmission electron microscopy vacuolar [DOI] 10.3389/fmed.2021.749318 PMC 바로가기 [Article Type] Medicine
Cryo-EM as a powerful tool for drug discovery: recent structural based studies of SARS-CoV-2Review Published on 2021-09-252022-10-27 Journal: Applied Microscopy [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome affecting ARDS binding coronavirus Cryo-electron microscopy cryo-EM death drug drug candidates drug design Drug discovery effective fragment-based drug discovery global pandemic help High-resolution in silico Infection Novel coronavirus pandemic powerful tool Protein Regulation Respiratory system rising SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Structure-based drug design syndrome therapeutic transmission electron microscopy [DOI] 10.1186/s42649-021-00062-x PMC 바로가기 [Article Type] Review
Development of a physiological model of human middle ear epitheliumOriginal Research Published on 2021-09-182022-10-30 Journal: The Laryngoscope [Category] COVID-19, [키워드] acute infection Antimicrobial therapy Biological models cells changed children ciliated clinical implication complex conditions Culture develop development disease Diseases epithelial epithelial cell epithelial cell type goblet immunofluorescence immunohistochemistry in vivo lack Level media membrane Microscopy mucosal otitis otitis media otorhinolaryngologic diseases physiological polymerase chain positive reflect Research respiratory mucosa Result Safe SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 shown subtype susceptible the healthy translational transmission electron microscopy Treatment undergo Ventilated [DOI] 10.1002/lio2.661 PMC 바로가기 [Article Type] Original Research