Spike-based COVID-19 immunization increases antibodies to nucleocapsid antigen스파이크 기반 COVID-19 면역은 뉴클레오캡시드 항원에 대한 항체를 증가시킵니다Article Published on 2022-02-012022-09-11 Journal: Translational research : the journal of laboratory [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] antibody Antibody Response Antibody responses Antigen avidity BNT162b2 C-terminus COVID-19 COVID-19 vaccination cross-reactive antibodies cross-reactive antibody detect full length Health care health care workers IgA IgG level IgG levels immunization immunoassay immunogenicity increase increase in individuals Infection MONITOR mRNA mRNA-1273 multiplex N antigen nucleocapsid nucleocapsid antigen Protein S-based vaccines SARS-CoV-2 S Seropositivity Subunit vaccine subunit vaccines suggested the SARS-CoV-2 vaccination Vaccine [DOI] 10.1016/j.trsl.2021.10.004 PMC 바로가기 [Article Type] Article
Seropositivity of SARS-CoV-2 IgG Antibody among People in Dhaka City during the Prevaccination Period사전 제거 기간 동안 다카시의 사람들 사이에서 SARS-COV-2 IgG 항체의 혈청 양성Research Article Published on 2022-01-272022-09-10 Journal: BioMed Research International [Category] 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus age Asymptomatic average baseline baseline data Blood Group blood sample Blood samples Chain Reaction city Community complementary coronavirus coronavirus disease coronavirus diseases COVID-19 determine effective enrolled Gender human body IgG IgG antibody IgG level IgG levels IgG positivity Immunoglobulin Immunoglobulin G indicate median no difference participant performed Period positive protocol reduce reduction respiratory RT-PCR SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibody Seropositivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 stratified tested Vaccine volunteers [DOI] 10.1155/2022/4451144 PMC 바로가기 [Article Type] Research Article
Humoral immunogenicity and tolerability of heterologous ChAd/BNT compared with homologous BNT/BNT and ChAd/ChAd SARS-CoV-2 vaccination in hemodialysis patients A multicenter prospective observational study혈액 투석 환자에서 동종 BNT/BNT 및 ChAd/ChAd SARS-CoV-2 백신 접종과 비교한 이종 ChAd/BNT의 체액 면역원성 및 내약성 다기관 전향적 관찰 연구Observational Study Published on 2022-01-272022-09-10 Journal: Journal of Nephrology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료법, [키워드] Abstract Adverse reaction Adverse reactions antibody appear AstraZeneca BNT BNT162b2 BNT162b2 vaccine ChAd ChAdOx1 ChAdOx1-nCoV-19 COVID-19 dose first dose first vaccination Hemodialysis Heterologous homologous Humoral immunity humoral immunogenicity IgG antibody IgG level IgG levels induce kidney limitation median mRNA-/vectored vaccines multicenter multivariable Multivariable regression analysis nCoV nucleocapsid observational study Patient patients percentile prospective observational study regression analysis Result SARS-CoV-2 SARS-CoV-2 spike IgG SARS-CoV-2 vaccination second dose severe adverse reactions Side effect Side effects significantly higher Tolerability vaccination Vaccine were assessed [DOI] 10.1007/s40620-022-01247-7 PMC 바로가기 [Article Type] Observational Study
Anti-SARS-CoV-2 antibody levels and kinetics of vaccine response: potential role for unresolved inflammation following recovery from SARS-CoV-2 infection항 -SARS-COV-2 항체 수준 및 백신 반응의 동역학 : SARS-COV-2 감염으로부터 회복 후 해결되지 않은 염증의 잠재적 역할Article Published on 2022-01-102022-09-01 Journal: Scientific Reports [Category] 바이오마커, 유전자 메커니즘, 진단, [키워드] administration anti-SARS-CoV-2 IgG antibody appear baseline best Biomarker BMI BNT162b2 BNT162b2 vaccine characterized circulating Cohort conditions CRP CRP level CRP levels Epidemiology Factors growth healthcare worker identify IgG level IgG levels immune response immunization Inflammation Inflammatory diseases Inter-individual variation kinetic Kinetics MCHC naïve subjects neutrophil neutrophil count pattern persistence positive Post-infection Post-vaccine Predictive markers Risk factors RNA vaccines SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine second dose subject subjects vaccination Vaccine viral infection with COVID-19 [DOI] 10.1038/s41598-021-04344-y PMC 바로가기 [Article Type] Article
Disease characteristics and serological responses in patients with differing severity of COVID-19 infection: A longitudinal cohort study in Dhaka, BangladeshCOVID-19 감염의 중증도가 다른 환자의 질병 특성 및 혈청 반응: 방글라데시 다카의 종단 코호트 연구Research Article Published on 2022-01-042022-09-12 Journal: PLoS Neglected Tropical Diseases [Category] 진단, [키워드] addition age age and sex analyzed antibody Antibody Response antibody response against Antibody responses Asymptomatic asymptomatic infection asymptomatic infections biochemical caused Characteristics clinician co-morbid condition co-morbid conditions Community conducted Control COVID-19 COVID-19 disease COVID-19 illness COVID-19 infection CRP CRP level CRP levels D-dimer disease disease severity Disease spectrum elevated enrolled Enrollment evaluate exclusion criteria ferritin ferritin level ferritin levels Follow-up visit follow-up visits Gender geographical region healthy healthy controls help hematological parameter hematological parameters hospital IgG antibodies IgG antibody IgG levels IgM and IgG immunological parameter immunological parameters infected individual Infection levels of antibody longitudinal cohort study longitudinal study lymphocyte lymphocyte counts male many cases Mild Mild disease moderate neutrophil neutrophil count NLR normal range Older age onset of symptom outcome outcomes participant Patient patients patients with COVID-19 predict progression RBD Receptor binding domain responsible risk factor Risk factors SARS-CoV-2 serological response seropositive Severe case severe cases severe COVID-19 disease severe COVID-19 illness severe disease severe disease manifestation severe patients severity of COVID-19 significantly higher Spike protein spike protein of SARS-CoV-2 the disease the spike protein Viral load [DOI] 10.1371/journal.pntd.0010102 PMC 바로가기 [Article Type] Research Article
Inactive SARS-CoV-2 vaccine generates high antibody responses in healthcare workers with and without prior infection비활성 SARS-CoV-2 백신은 감염 여부에 관계없이 의료 종사자에게 높은 항체 반응을 생성합니다.Article Published on 2022-01-032022-09-11 Journal: Vaccine [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] 95% CI Abbott age Anti-spike antibody Antibody Response Antibody titers approach benefit cellular immune responses Chemiluminescent microparticle immunoassay China CMIA CoronaVac COVID-19 Dilution dose effective faculty female first dose generate group HCW HCWs healthcare worker Healthcare workers humoral Humoral and cellular immune responses Humoral immunity hypertension IgG IgG level IgG levels immune responses immunoassay inactive Infection İstanbul life male material Microparticle monitoring neutralization test Participants Patient plaque reduction neutralization Plaque reduction neutralization test PRNT required SARS-CoV-2 vaccine second dose significantly higher significantly lower Sinovac Life Sciences Spread study group the anti-spike/RBD antibody. Turkey USA vaccination Vaccine variants was used were measured [DOI] 10.1016/j.vaccine.2021.11.051 PMC 바로가기 [Article Type] Article
Determinants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naïve healthcare workers노출되고 순진한 의료 종사자 집단에서 COVID-19 mRNA 백신에 대한 초기 항체 반응의 결정 요인Clinical Trial Published on 2022-01-012022-09-11 Journal: EBioMedicine [Category] 변종, 임상, 진단, 치료기술, 치료법, [키워드] 95% CI Adults adverse events Affect allergy Alpha Analysis analyzed antibody Antibody avidity antibody levels Antibody Response Antigen antigens avidity Barcelona Beta BNT162b2 brand center Cohort Comorbidities Comorbidity COVID-19 COVID-19 mRNA vaccine Daniel Data collection days post-infection decision determinant development dose Effectiveness Efficacy European evaluated expected Factor Gamma had no Health care Health care worker health care workers healthcare worker healthy individual heterogeneity IgA IgG IgG and IgM IgG level IgG levels Immunity indicate Infectious disease Infectious diseases Influenza Innovation maintenance manuscript Moderna mRNA mRNA vaccination mRNA vaccines mRNA-1273 naïve neutralization neutralization capacity neutralizing capacity nucleocapsid omicron Pfizer/BioNTech preparation Program reagent receiving recommendation respond response responsiveness robust SARS-CoV-2 SARS-CoV-2 spike Science second dose seropositive Severo Ochoa shown Single-dose smoking Spanish state Study design Support supported symptomatic systemic adverse effect systemic adverse effects technology the preparation union vaccination vaccine doses vaccinees variant variants variants of concern wild-type [DOI] 10.1016/j.ebiom.2021.103805 PMC 바로가기 [Article Type] Clinical Trial
Humoral Response to Pfizer BNT162b2 Vaccine Booster in Maintenance Hemodialysis Patients유지 혈액투석 환자에서 화이자 BNT162b2 백신 부스터에 대한 체액 반응Article Published on 2022-01-012022-09-11 Journal: American journal of nephrology [Category] SARS, 치료법, [키워드] administration adverse effect antibody Antibody titer Antibody titers association BNT162b2 BNT162b2 vaccine booster booster dose Breakthrough infection control group coronavirus disease COVID-19 COVID-19 vaccine COVID-19 virus decrease determine disease dose excluded Hemodialysis humoral Humoral response IgG level IgG levels inflammation markers maintenance Maintenance hemodialysis Malnutrition marker morbidity and mortality observation observations Patient patients Pfizer Pfizer-BioNTech positive antibody response positive PCR positively correlated receive recent reported response resulting SARS-CoV-2 significantly higher sustained Vaccine [DOI] 10.1159/000521676 PMC 바로가기 [Article Type] Article
Antibody response after one and two jabs of the BNT162b2 vaccine in nursing home residents: The CONsort-19 study요양원 거주자의 BNT162b2 백신 1회 및 2회 접종 후 항체 반응: CONsort-19 연구Article Published on 2022-01-012022-09-11 Journal: Allergy [Category] SARS, 진단, 치료법, [키워드] Analysis antibodies against SARS-CoV-2 antibody BNT162b2 BNT162b2 vaccine BNT162b2/Pfizer vaccine Chain Reaction COVID-19 COVID-19 infection COVID-19 vaccination diagnosed First wave French higher risk highest humoral immune response IgG IgG antibodies IgG antibody IgG level IgG levels Infection longitudinal study MOST N-protein nucleocapsid nursing home nursing homes Older polymerase chain polymerase chain reaction Post-vaccine Protein RBD IgG Real-time reverse-transcriptase polymerase chain reaction remained resident rRT-PCR RT-PCR S-RBD SARS-CoV-2 seronegative seropositive single vaccine Spike protein symptomatic symptomatic COVID-19 the spike protein vaccination were measured [DOI] 10.1111/all.15007 PMC 바로가기 [Article Type] Article
Infection With the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta Variant Is Associated With Higher Recovery of Infectious Virus Compared to the Alpha Variant in Both Unvaccinated and Vaccinated Individuals중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 델타 변이형 감염은 백신 접종을 받지 않은 사람과 백신을 맞은 사람 모두에서 알파 변이형에 비해 감염성 바이러스의 더 높은 회복률과 관련이 있습니다Major Article Published on 2021-12-182022-09-10 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료제, [키워드] (alpha acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Alpha variant anti-SARS-CoV-2 antibody Antiviral B.1.1.7 B.1.617.2 breakthrough infections Capital Capital Region Cell culture circulating clinical chart Cohort Comorbidities coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 cycle threshold Delta delta variant disease severity greater transmissibility groups IgG IgG levels Immunoglobulin Immunoglobulin G increase in Increases increases in individual Infection infections Infectious virus Lineage Local nasal predominant Region respiratory Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 lineage severe acute respiratory syndrome Coronavirus significant increase significantly higher specimens symptomatic the median vaccinated individual vaccinated individuals vaccination variant variants Viral Viral RNA virus VoC Whole genome sequencing [DOI] 10.1093/cid/ciab986 PMC 바로가기 [Article Type] Major Article