Mass spectrometric identification of immunogenic SARS-CoV-2 epitopes and cognate TCRs
면역원성 SARS-CoV-2 에피토프 및 동족 TCR의 질량 분석 식별
420
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
Analysis
approach
best
binding affinities
caused
cell lines
cells
cellular immune responses
conserved
coronavirus
COVID-19
COVID-19 infection
Critical
defined
effective
elicit
epitope
Epitopes
Evidence
expressing
glycoprotein
histocompatibility complex
humoral
Humoral response
humoral responses
immune
immune protection
immune responses
immunogenic
immunogenicity
In silico method
in vitro
increasingly
Infection
infectious
kill
killing
major histocompatibility complex
malignant disease
malignant diseases
mass spectrometric
mass spectrometry
membrane
membrane glycoprotein
MGP
MHC
MHC peptide
nsp13
peptide
peptides
predict
processed
Protein
recognize
recognizing
Region
reported
respiratory
robust
SARS-CoV-2
SARS-CoV-2 antigen
SARS-CoV-2 epitope
SARS-CoV-2 epitopes
SARS-CoV-2 peptide
SARS-CoV-2 strains
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
Significance
specificity
T cell
T cell epitope
T cell epitopes
T cell response
T cell responses
T cells
tandem
Tandem mass spectrometry
target cells
TCR
TCR-T
the disease
the SARS-CoV-2
therapy
to define
Treatment
variants
[DOI] 10.1073/pnas.2111815118 PMC 바로가기 [Article Type] 420
[DOI] 10.1073/pnas.2111815118 PMC 바로가기 [Article Type] 420