Health-Related Quality of Life and Experiences of Brazilian Celiac Individuals over the Course of the Sars-Cov-2 PandemicClinical Trial Published on 2021-05-092022-10-04 Journal: Nutrients [Category] SARS, 임상, [키워드] addition Affect affected age caused celiac disease children collected concerning conducted consequence Course COVID-19 COVID-19 pandemic cross-sectional death disease evaluate experience Health increased the risk individual inherent life measure not affect outbreak outcome pandemic Pandemics patients Positive test psychological pressure Quality Quality of life questionnaire Research responses Spread subsequent [DOI] 10.3390/nu13051582 PMC 바로가기 [Article Type] Clinical Trial
Impact of the COVID-19 Pandemic on Oncology Clinical Research in Latin America (LACOG 0420)COVID-19 전염병이 라틴 아메리카의 종양학 임상 연구에 미치는 영향(LACOG 0420)ORIGINAL REPORTS Published on 2021-05-062022-09-10 Journal: JCO Global Oncology [Category] MERS, 임상, [키워드] adopted affected alteration Brazil Cancer Care change clinical Clinical research clinical trial clinical trials confirmed COVID-19 case Cooperative COVID-19 COVID-19 cases COVID-19 mitigation COVID-19 pandemic cross-sectional cross-sectional study diagnostic drug evaluate Follow-up Formal group home office Impact improvement Improvements increase in institution knowledge Latin Latin America majority management novel oncology Patient patients reduction regions remote monitoring Research responses selected site initiation Sponsor suggested Telemedicine telemedicine visits Treatment Trial [DOI] 10.1200/GO.20.00663 PMC 바로가기 [Article Type] ORIGINAL REPORTS
Type I and III interferon responses in SARS-CoV-2 infectionSARS-CoV-2 감염에서 I형 및 III형 인터페론 반응Review Published on 2021-05-062022-09-10 Journal: Experimental & Molecular Medicine [Category] SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activity Antiviral effect antiviral effects block caused cellular response Cellular responses contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill critically ill patients Cytokines Defense element elements evade exacerbate explain expression Extensive Host host protein host proteins hyper-inflammation IFN IFN pathways IFNs immune cells immune system Immune system dysfunction IMPROVE infected cells Infection Infectious diseases Inflammation Inflammatory response Inflammatory responses influence inhibit innate cytokine innate cytokines interferon response interferons interferons (IFNs mechanism non-infected pandemic disease Patient progression researcher respiratory response responses robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein SARS-CoV-2 proteins Science severe acute respiratory syndrome Coronavirus severe COVID-19 Shin South Korea technology treatments for COVID-19 triggered Type type I type I and III IFNs type I and III interferons type I and type III interferons Type I IFN type I IFN responses type III interferon viruses [DOI] 10.1038/s12276-021-00592-0 PMC 바로가기 [Article Type] Review
Multifaceted Role of AMPK in Viral InfectionsReview Published on 2021-05-062022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] AMPK anabolic processes Apoptosis autophagy catabolic process Cell change COVID-19 COVID-19 pandemic effective facilitate fatty fatty acid metabolism growth highlight homeostasis Host host cell immune function Infection inhibit lipid metabolism mitochondrial mitochondrial homeostasis modulation pathogen physiological conditions proliferation Protein Regulation Regulatory responses role Signaling signaling pathway Stress suggested survival therapeutic strategy viral infectious diseases viral replication virus [DOI] 10.3390/cells10051118 PMC 바로가기 [Article Type] Review
Probiotic-Based Vaccines May Provide Effective Protection against COVID-19 Acute Respiratory DiseaseReview Published on 2021-05-062022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome addition adjuvants Administered administration approach Cell-mediated immune responses clinical information codon usage concern coronavirus COVID-19 cross-talk dose Effectiveness elicit Emergency expression level highlight IgA antibody immune response immune responses immune system induce Infection infections microorganism microorganisms modulating modulation mucosal mucosal immune Mucosal immunization mucosal route nasal neutralize previous study Probiotics Prospective Study protection Protective Public respiratory responses SARS-CoV-2 SARS-COV-2 infection serum IgG shown Therapeutic molecule therapeutic molecules therapy transmitted Vaccine development Vaccines vectors virus viruses WHO World Health Organization [DOI] 10.3390/vaccines9050466 PMC 바로가기 [Article Type] Review
Treatment provision for adults with ADHD during the COVID-19 pandemic: an exploratory study on patient and therapist experience with on-site sessions using face masks vs. telepsychiatric sessionsResearch Published on 2021-05-052022-10-27 Journal: BMC Psychiatry [Category] Coronavirus, SARS, [키워드] adjusted Affect analyses aspect Attention-deficit/hyperactivity disorder (ADHD) benefit Care change collected conducted COVID-19 COVID-19 pandemic disorder Effectiveness elements exploratory exploratory study Face mask face-to-face sessions Face-to-face treatment First wave identify Intervention less maintaining Multiple regression Patient patient questionnaire problem Psychiatric Psychiatric disorders qualitative data Quantitative questionnaire data reported required Research responses Result Satisfaction significantly statistically significant difference supplementary material Switzerland Symptom telephone telepsychiatry therapeutic therapeutic alliance therapy Treatment utility videoconferencing were used while [DOI] 10.1186/s12888-021-03236-9 PMC 바로가기 [Article Type] Research
Air Quality During COVID-19 Lockdown in the Yangtze River Delta and the Pearl River Delta: Two Different Responsive Mechanisms to Emission Reductions in ChinaObservational Study Published on 2021-05-042022-10-05 Journal: Environmental science & technology [Category] SARS, 임상, [키워드] aerosol Aerosols anthropogenic activity average China Clusters COVID-19 Delta discrepancy emission NOx Observational data opposite outbreak PEARL PrD primary pollutant Quality reached reduction reduction in regions responses river stationary Transport Yangtze River Delta [DOI] 10.1021/acs.est.0c08383 PMC 바로가기 [Article Type] Observational Study
Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model죽은 전체 게놈 감소 박테리아 표면 발현 코로나 바이러스 융합 펩티드 백신은 돼지 모델에서 질병으로부터 보호합니다423 Published on 2021-05-042022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 진단, [키워드] Amino acid amino acid residues anamnestic response Bacteria Bacterial Betacoronavirus Cell cell surface clinical disease conserved core coronavirus coronavirus disease Coronavirus disease 2019 coronavirus vaccine COVID-19 cross-protection demonstrated diarrhea disease downstream Efficacy elicited ENhance epidemic diarrhea Escherichia coli evaluated Express expressing expression vector fusion peptide genome-reduced bacteria vaccine platform highly conserved fusion peptide immune system Immunity Interaction interferon interferon-γ offer pandemic Pathogens PEDV peptide PIGS platform porcine epidemic diarrhea virus (PEDV) principle proof PROTECT Protective provide provided reduced residue responses SARS-CoV-2 sequence Significance sterilizing immunity target tested tissue Transport upstream utility Vaccine vaccine antigen vaccine immunogenicity vaccine platform Vaccines viral RNA load virus whole-genome [DOI] 10.1073/pnas.2025622118 PMC 바로가기 [Article Type] 423
Evolution of psychosocial burden and psychiatric symptoms in patients with psychiatric disorders during the Covid-19 pandemicOriginal Paper Published on 2021-05-032022-10-31 Journal: European archives of psychiatry and clinical neuro [Category] COVID-19, MERS, [키워드] adaptive Adjustment Adjustment disorder Bonferroni-corrected burden condition coronavirus Course diagnose Effect exhibited female patient Gender ICD-10 Impact initial inventory Local lockdown lockdown restriction Mental disorder Mental Disorders mental health mental health issue module MOST New Pairwise comparison pandemic Patient Psychiatric psychiatric disorder Psychosocial stress remained Resilience responses risk risk factor SARS-CoV-2 specific treatment Stress supplementary material Symptom Symptoms worsening [DOI] 10.1007/s00406-021-01268-6 PMC 바로가기 [Article Type] Original Paper
Comparative analysis of antibodies to SARS-CoV-2 between asymptomatic and convalescent patientsArticle Published on 2021-05-012022-10-30 Journal: iScience [Category] COVID-19, [키워드] Abstract ACE2 binding analyzed Anti-RBD IgG anti-S antibody antibody cross-reactivity Antibody Response Asymptomatic asymptomatic individual Asymptomatic individuals Comparative analysis convalescent patient coronavirus correlation COVID-19 COVID-19 patient cross-reactivity develop effective Health healthy individual highest IgG IgG antibody immune response Immunological response immunology Increased individual Infection control in health technology pandemic positive post vaccination protective immunity Protein RBD Responder responses responses against robust SARS-CoV-2 SARS-CoV-2 antibody response SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 symptomatic patient SARS-CoV-2 viral screened Southeastern United State spike tested Treatment Vaccines Virology were assessed without symptom without symptoms [DOI] 10.1016/j.isci.2021.102489 PMC 바로가기 [Article Type] Article