Sharing a household with children and risk of COVID-19: a study of over 300 000 adults living in healthcare worker households in Scotland어린이와 함께 가구 공유 및 Covid-19의 위험Original Research Published on 2021-12-182022-09-10 Journal: Archives of Disease in Childhood [Category] SARS, 유전자 메커니즘, [키워드] 95% CI adjusted association Child children cohort study Contact contact with COVID COVID-19 Epidemiology Evidence exposure to healthcare worker hospitalisation house household household contact investigated less National Health Service number objective outcome over parent Positive test potential mechanisms reduce reduced respiratory respiratory viral infections Result risk risk of COVID-19 SARS-CoV-2 School Schools setting statistically significant study period study population Viral was reduced [DOI] 10.1136/archdischild-2021-321604 PMC 바로가기 [Article Type] Original Research
Dried blood spot specimens for SARS-CoV-2 antibody testing: A multi-site, multi-assay comparisonSARS-CoV-2 항체 검사를 위한 건조 혈반 표본: 다중 부위, 다중 분석 비교Comparative Study Published on 2021-12-072022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] 95% CI Blood Canada COVID-19 diagnostic diagnostic testing estimates foundation gold gold standard greater Health policy house Implementing Laboratory NAAT Negative predictive value nucleic acid nucleic acid amplification performed positive Positive predictive value Predictive value Prevalence public health representing SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody sensitivity Serological assay serological assays serological test Serological tests Severity of infection specificity specimen tested unique validation study [DOI] 10.1371/journal.pone.0261003 PMC 바로가기 [Article Type] Comparative Study
Antibody response to the first dose of AZD1222 vaccine in COVID-19 convalescent and uninfected individuals in Bangladesh방글라데시에서 COVID-19 회복기 및 감염되지 않은 개인에서 AZD1222 백신의 첫 번째 접종에 대한 항체 반응Article Published on 2021-12-012022-09-11 Journal: Expert review of vaccines [Category] 진단, 치료법, [키워드] Antibody Response Antibody test antibody tests Antibody titer Antibody titers AZD1222 benefit convalescence convalescent convalescent individual COVID-19 COVID-19 vaccine Day dose elevated first dose Healthcare system house IgA IgG IgM in-house ELISA individual Infection integration nine Oxford Oxford-AstraZeneca profiles SARS-CoV-2 Seroconversion subject the antibody response two groups uninfected vaccination Vaccine [DOI] 10.1080/14760584.2021.1977630 PMC 바로가기 [Article Type] Article
Recognition of Variants of Concern by Antibodies and T Cells Induced by a SARS-CoV-2 Inactivated VaccineSARS-COV-2 불활성 백신에 의해 유도 된 항체 및 T 세포에 의한 관심의 변이체 인식Clinical Trial Published on 2021-11-092022-08-13 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition Alpha antibodies antibody approved B.1.1.7 B.1.351 Beta Beta variant binding cellular response Cellular responses Chilean circulating variant clinical trial concern CoronaVac coronavirus D614G death rate Delta delta variant described detect dose elicited ELISPOT enrolled evaluate evaluated Gamma genetic difference genetic differences geometric mean Geometric means house human ACE2 receptor immune response immunization immunization schedule immunization schedules immunized immunogenic in-house ELISA inactivated induced Infection interferon interferon-γ-secreting T cell interferon-γ-secreting T cells Lineage microneutralization neutralization neutralize Neutralizing antibodies neutralizing antibody neutralizing capacity P.1 pandemic PBMC PBMCs Phase 3 phase 3 clinical trial promote Protective RBD Receptor binding domain Recognition reduced respiratory responsible Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants secreted secretion Seropositivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown significant differences spike stimulate subject T cell immunity T cells tested the RBD the SARS-CoV-2 the vaccine titers Vaccine variant variants variants of concern virus Volunteer volunteers were used Wuhan Wuhan, China [DOI] 10.3389/fimmu.2021.747830 PMC 바로가기 [Article Type] Clinical Trial
High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort브라질 마나우스의 2차 유행 이전 높은 항 SARS-CoV-2 항체 혈청 전환율 및 사회적 행동 조치의 보호 효과: 전향적 DETECTCoV-19 코호트의 결과Article Published on 2021-11-012022-09-11 Journal: The Lancet. Global health [Category] MERS, SARS, 진단, 치료법, [키워드] 95% CI adjusted analyses Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody association Asymptomatic baseline Brazil calculated city Cohort Comorbidities Compliance Contact contact with COVID-19 COVID-19 case COVID-19 diagnosis COVID-19 pandemic criteria defined disease status education event first visit flu-like symptom flu-like symptoms Follow-up follow-up period had no Health Health Organization health system house household IgG antibody implementation in-house ELISA incidence incidence rate Increased increased the risk Infection transmission information Intervention IQR Mask measure Measures median negative control nucleocapsid optical optical density organization Pan participant physical distancing Poisson regression model positive proportion Protective Protective behaviours protective effect rate ratios reactivity recruited Relaxation reported returned risk factor Risk factors second wave separated Seroconversion seroconversion rate seronegative seropositive serum Sociodemographic characteristics study cohort study period symptomatic Symptoms the epidemic Transmission variable was measured website were excluded with COVID-19 [DOI] 10.1016/S2214-109X(21)00355-7 PMC 바로가기 [Article Type] Article
Near-Complete Genome of SARS-CoV-2 Delta (AY.3) Variant Identified in a Dog in Kansas, USASARS-COV-2 델타의 거의 완전한 게놈 (AY.3) 변형은 미국 캔자스의 개에서 확인Article Published on 2021-10-192022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis animal AY.3 canine change characterization Cluster coding region Collie Consensus coronavirus COVID-19 COVID-19 disease Delta delta variant description dog house Human Identified infecting Infection Local outbreak Phylogenetic positive respiratory SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants sequence sequenced severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 susceptibility Symptom tested Transmission underlying conditions unique USA variant virus whole genome sequence [DOI] 10.3390/v13102104 PMC 바로가기 [Article Type] Article
Quantifying SARS-CoV-2 nucleocapsid antigen in oropharyngeal swabs using single molecule array technology단일 분자 어레이 기술을 사용하여 구인두 면봉에서 SARS-CoV-2 뉴클레오캡시드 항원 정량화Article Published on 2021-10-132022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료법, [키워드] 95% CI ambition analyzed Antigen Biochemistry can be used clinical sensitivity clinically comparable correlated Culture cut-off demonstrated develop house lysis buffer Microbiology nucleocapsid antigen oropharyngeal swab oropharyngeal swabs Point positive real time real-time RT-PCR reference method routine clinical practice RT-PCR Sample SARS-CoV-2 SARS-CoV-2 infected patient SARS-CoV-2 infected patients SARS-CoV-2 nucleocapsid SARS-CoV-2 RNA SARS-CoV-2 virus sensitivity Simoa specificity Testing treated virus culture was used [DOI] 10.1038/s41598-021-99807-7 PMC 바로가기 [Article Type] Article
An international comparison of anti-SARS-COV-2 assays used for seroprevalence surveys from blood component providers혈액 성분 제공자의 혈청유병률 조사에 사용되는 항 SARS-COV-2 분석의 국제 비교Article Published on 2021-10-012022-09-11 Journal: Vox Sanguinis [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제, [키워드] Abbott Abbott SARS-CoV-2 IgG access adjust Affect anti-SARS-CoV-2 antibody Antigen Blood blood component suppliers blood donor Blood donors blood supplier blood suppliers Characteristics country COVID-19 pandemic detect Diversity Donor estimates evaluate FIVE healthy highlight house identity IgG IgM Immunoglobulin information International material methodology nucleocapsid protein operator operators optimization provided ranged responses SARS-CoV-2 sensitivity Sensitivity and specificity serology assay Seroprevalence seroprevalence survey specificity Spike protein survey the spike protein Viral Viral proteins while [DOI] 10.1111/vox.13100 PMC 바로가기 [Article Type] Article
Prevalence of IgG antibodies induced by the SARS-COV-2 virus in asymptomatic adults in Nuevo Leon, Mexico멕시코 누에보레온의 무증상 성인에서 SARS-COV-2 바이러스에 의해 유도된 IgG 항체의 유병률Article Published on 2021-10-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 진단, 치료법, [키워드] 95% CI 95% confidence interval Adults age analyzed Asymptomatic asymptomatic individual Asymptomatic individuals carried coronavirus COVID-19 COVID-19 vaccine cross-sectional cross-sectional study Diagnosis distribution eligible Evidence evidence of Geographic distribution highest house IgG IgG antibodies IgG antibody Immunoglobulin Immunoglobulin G individual Latin America MOST no difference no differences nucleocapsid protein Prevalence preventive measure preventive measures previous diagnosis promotion Protein reported SARS-COV-2 infection SARS-CoV-2 nucleocapsid SARS-CoV2 screened Seroprevalence Sex Symptom virus was done Week [DOI] 10.1002/jmv.27131 PMC 바로가기 [Article Type] Article
Comparison of analytical sensitivity of SARS-CoV-2 molecular detection kitsSARS-CoV-2 분자 검출 키트의 분석 감도 비교Article Published on 2021-10-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analytical sensitivity approved assays assist clinics Concentration coronavirus detection Epidemic evaluate global public health help house IMPROVE Infection Laboratory limit of detection limits Limits of detection molecular molecular detection National Medical Products Administration nucleic acid Nucleic acid detection PCR Prevention and control product ranged real-time reverse transcriptase required Research reverse transcriptase Ribonucleic acid rRT-PCR SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 were used [DOI] 10.1016/j.ijid.2021.08.043 PMC 바로가기 [Article Type] Article