Myocardial Involvement in COVID-19: an Interaction Between Comorbidities and Heart Failure with Preserved Ejection Fraction. A Further Indication of the Role of InflammationComorbidities of Heart Failure (J. Tromp, Section Editor) Published on 2021-04-222022-10-31 Journal: Current heart failure reports [Category] COVID-19, MERS, SARS, [키워드] abnormality Activation Affect association cardiac Cardiomyopathy cause Chronic kidney disease Comorbidity Course COVID-19 COVID-19 patient diabetes diastolic disease dysfunction echocardiographic Ejection Ejection fraction failure fibrosis healthy heart heart failure Heart failure with preserved ejection fraction HFpEF hospitalized patient hypertension impairment independent risk factor indication Inflammatory Involvement majority Myocardial inflammation obesity Patient patients predictor preserved Prevalence pro-inflammatory state pulmonary hypertension recent reveal risk role SARS-COV-2 infection the disease ventricular dysfunction with COVID-19 [DOI] 10.1007/s11897-021-00509-y PMC 바로가기 [Article Type] Comorbidities of Heart Failure (J. Tromp, Section Editor)
The Involvement of MicroRNAs in SARS-CoV-2 Infection Comorbid with HIV-Associated PreeclampsiaHIV 관련 자간전증을 동반한 SARS-CoV-2 감염에서 MicroRNA의 관련성Review Published on 2021-04-132022-09-11 Journal: Current hypertension reports [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Anti-viral coronavirus Critical demonstrated Diseases Disruption downregulate dysregulated Epigenetic Evidence evidence of expression foundation Health HIV HIV-1 HIV-1 infection Host host miRNA Human Human immunodeficiency virus hypertension immunodeficiency immunodeficiency virus implicated in silico in viral Infection investigated involved Involvement Maternal mechanism microRNA MicroRNAs miRNA miRNAs physiological physiological change preeclampsia Pregnancy pregnant women prevalent Protein provided recent Regulatory Research SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Side-effect silico studies South Africa synergy therapeutic viral infections women [DOI] 10.1007/s11906-021-01138-5 PMC 바로가기 [Article Type] Review
Systemic Inflammation Is Associated With Neurologic Involvement in Pediatric Inflammatory Multisystem Syndrome Associated With SARS-CoV-2전신 염증은 SARS-CoV-2와 관련된 소아 염증성 다기관 증후군의 신경학적 관여와 관련이 있습니다Article Published on 2021-04-132022-09-11 Journal: Neurology® neuroimmunology & neuroinflammation [Category] MERS, 바이오마커, [키워드] Abnormalities Asian behavioral changes black change changes children Children's Hospital cranial CRP D-dimer D-dimers died disorder Ethnicity feature ferritin fibrinogen Follow-up full recovery Hallucination headache Headaches hemiparesis highest hospital Immune-mediated Inflammatory Involvement marker neurologic Neurologic impairment not recovered obese outcome overweight Patient performed PIMS presenting procalcitonin prothrombotic retrospective risk factor SARS-CoV-2 Seizure Seizures Symptoms syndrome systemic systemic inflammatory marker [DOI] 10.1212/NXI.0000000000000999 PMC 바로가기 [Article Type] Article
Involvement of Interleukin-1 Receptor-Associated Kinase 4 and Interferon Regulatory Factor 5 in the Immunopathogenesis of SARS-CoV-2 Infection: Implications for the Treatment of COVID-19Immunology Published on 2021-04-072022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, [키워드] “cytokine storm” activated Adaptive immunity chemokine COVID-19 cytokine Cytokine storm Factor hyperinflammatory state IL-1 inhibitor innate immune response Innate immunity interferon regulatory factor interleukin-1 Involvement irak4 IRF5 kinase Ligand M1 macrophages membranes microbial infection morbidity and mortality NF-κB Pellino-1 plasma potential therapy Proinflammatory cytokine receptor required SARS-CoV-2 signaling pathway synergistic TLR transcription factors [DOI] 10.3389/fimmu.2021.638446 PMC 바로가기 [Article Type] Immunology
COVID-19 in Children: Respiratory Involvement and Some Differences With the AdultsPediatrics Published on 2021-03-292022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute respiratory distress ARDS can be used children complex mechanism coronavirus disease COVID-19 decrease develop Diagnosis difference explain Health heterogeneous Impact IMPROVE Interaction Involvement knowledge less majority mechanism morbidity MOST multidimensional Patient pediatric Pneumonia respiratory respiratory compromise respiratory involvement respiratory manifestation Respiratory system SARS-CoV-2 severe cases severity syndrome the disease Treatment [DOI] 10.3389/fped.2021.622240 PMC 바로가기 [Article Type] Pediatrics
Association of Blood Subgroups With PCR Test Positivity and Lung Involvement in Patients With COVID-19Internal Medicine Published on 2021-03-292022-10-31 Journal: Cureus [Category] COVID-19, [키워드] ABO Blood Group Blood groups comparison consecutive patient COVID-19 COVID-19 infection distribution Infection Involvement lung involvement Negative PCR objective Patient PCR PCR positivity performed polymerase chain positive positive PCR result positive PCR test Precaution Result risk of COVID-19 SARS-CoV-2 significant difference Symptom Test the patient with COVID-19 [DOI] 10.7759/cureus.14172 PMC 바로가기 [Article Type] Internal Medicine
Ocular Involvement of SARS-CoV-2 in a Polish Cohort of COVID-19-Positive Patients폴란드 COVID-19 양성 환자 집단에서 SARS-CoV-2의 안구 침범Article Published on 2021-03-122022-09-10 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, [키워드] affected age characterized coronavirus coronavirus SARS-CoV-2 correlation COVID-19 COVID-19 pandemic detectable disease Efficiency enrolled eye eyes genetic material hospital Infection Involvement lung Lung disease male nasopharyngeal Occurrence ocular ocular symptoms organ Patient PCR positive presenting respiratory respiratory symptoms responsible SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus shown Support Swab swabs Symptom Symptoms tested the SARS-CoV-2 the SARS-CoV-2 virus tropism [DOI] 10.3390/ijerph18062916 PMC 바로가기 [Article Type] Article
The Good Treatment, the Bad Virus, and the Ugly Inflammation: Pathophysiology of Kidney Involvement During COVID-19Physiology Published on 2021-03-112022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] ACE2 AKI (acute kidney injury) antiviral drug association Autopsy biopsies cells COVID COVID-19 COVID–19 critically ill patients cytopathogenic effect described direct viral infection endothelial cells ENhance event Good help highlight immunomodulators Infection Inflammation Involvement kidney kidneys mechanism Multi-organ damage observational studies organ dysfunction outcomes pathophysiological hypotheses Perspective raise reflect renal renal damage responsible SARS – CoV – 2 SARS-CoV-2 SARS-COV-2 infection sequence Spread Structure synergy systemic inflammation target Therapeutic strategies tissue TMPRSS2 viral invasion viral pathogenicity viral sepsis virus while [DOI] 10.3389/fphys.2021.613019 PMC 바로가기 [Article Type] Physiology
Low Sensitivity of Admission Lung US Compared to Chest CT for Diagnosis of Lung Involvement in a Cohort of 82 Patients with COVID-19 PneumoniaCOVID-19 폐렴 환자 82명 코호트에서 폐 침범 진단을 위한 흉부 CT와 비교한 입원 폐 US의 낮은 민감도Article Published on 2021-03-042022-09-10 Journal: Medicina [Category] SARS, 진단, 치료기술, [키워드] (Computed Tomography Abnormalities abnormality Admission calculated Chest-CT clinical evaluation Computed tomography consolidation coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia crazy-paving pattern CT finding CT findings Department detect diagnostic test diagnostic tests disease Emergency emergency department Ground-glass opacities ground-glass opacity hospital integration interstitial pneumonia Involvement lung lung involvement lung ultrasound (LUS) Mild Mild disease moderate disease Nasopharyngeal swab objective Patient performed Pneumonia presenting pulmonary lesion pulmonary lesions ranged recruited reference standard Result SARS-CoV-2 SARS-CoV-2 pneumonia sensitivity severe disease subpleural with COVID-19 zone [DOI] 10.3390/medicina57030236 PMC 바로가기 [Article Type] Article
Involvement of Oxidative Stress and the Innate Immune System in SARS-CoV-2 InfectionReview Published on 2021-02-242022-11-01 Journal: Diseases [Category] COVID-19, [키워드] acute respiratory syndrome affected affecting antioxidant Asymptomatic China Chronic diseases Cytokine storm drug excessive inflammation Factor Factors fatal disease groups Healthcare system immune system impacted individuals infected individual Innate Innate immunity Involvement Macrophage majority mechanism Novel coronavirus obese other coronavirus oxidative stress pandemic pathogen Patient patients potential risk presenting recent finding Research Respiratory system responsible risk risk factor SARS-CoV-2 SARS-COV-2 infection severe disease course severe symptom Spread Stress System target Transmission virus [DOI] 10.3390/diseases9010017 PMC 바로가기 [Article Type] Review