SEAMHCRD deterministic compartmental model based on clinical stages of infection for COVID-19 pandemic in Sultanate of OmanArticle Published on 2021-06-072022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] Analysis basic reproduction number Clinical stage compartmental model Computational science Contact COVID-19 COVID-19 pandemic disease effective Final Generation identify infected individual Infection Mathematics and computing matrix Novel coronavirus Oman pandemic parameter parameters performed predicted recognize reported Research Spread stability Stage symptomatic the disease Transmission worldwide crisis [DOI] 10.1038/s41598-021-91114-5 PMC 바로가기 [Article Type] Article
Generation of restriction endonucleases barcode map to trace SARS-CoV-2 origin and evolutionArticle Published on 2021-06-032022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] approach China classical coronavirus genome endonuclease Evidence Evolution Generation genetic manipulation genetic mapping Genome human SARS-CoV-2 Molecular biology observation restriction site SARS-CoV-2 sequence viral infection virus [DOI] 10.1038/s41598-021-91264-6 PMC 바로가기 [Article Type] Article
Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based ApproachArticle Published on 2021-05-182022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] abnormality Accuracy acute respiratory distress affected Algorithm approach ARDS caused chest X-ray CNNs Contact COVID-19 COVID-19 detection COVID-19 virus CXR dataset deep deep learning detect detection develop discharge disease feature Feature selection generate Generation generative adversarial network harmony Harmony Search help identify Image individual initial screening learning limit limitations lung Mild symptom MOST nasal network Neural organ overcome performed positive Radiographic reduce Saliva Spread syndrome synthetic synthetic data generation the SARS-CoV-2 virus X-ray [DOI] 10.3390/diagnostics11050895 PMC 바로가기 [Article Type] Article
Rotavirus as an Expression Platform of Domains of the SARS-CoV-2 Spike ProteinArticle Published on 2021-05-032022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Administered cassette children coding coding sequence COVID-19 vaccine domain double-stranded RNA expected Express expressed expression vector feasibility FLAG-tagged full-length S gastroenteritis Generation Genome highest immunoblotting immunogenic insertion introduced kDa N-terminal domain NTD RBD Reoviridae required reverse genetics RNA rotavirus rotavirus vaccine S protein S-protein SARS-CoV-2 sequence spike Spike protein the SARS-CoV-2 translational Vaccine variant virus [DOI] 10.3390/vaccines9050449 PMC 바로가기 [Article Type] Article
Frontline Screening for SARS-CoV-2 Infection at Emergency Department Admission by Third Generation Rapid Antigen Test: Can We Spare RT-qPCR?3세대 신속 항원 검사를 통한 응급실 입원 시 SARS-CoV-2 감염에 대한 최전선 검사: RT-qPCR을 절약할 수 있습니까?Article Published on 2021-05-012022-09-01 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] 95% CI active viral replication acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission antigenic test Can Clinical use complement coronavirus country COVID-19 cycle threshold demonstrated Department Diagnosis diagnostic digital PCR droplet Emergency emergency department expected false-negative Generation genomic hospital increase infections Infectivity introduced IQR lack median Nasopharyngeal swab nasopharyngeal swabs Patient PCR persists qPCR quantification Rapid Rapid antigen tests Rapid diagnostic test respiratory risk RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA Screening sensitivity severe acute respiratory syndrome Coronavirus specificity subgenomic RNA subject suggested the WHO Viral Viral load [DOI] 10.3390/v13050818 PMC 바로가기 [Article Type] Article
Generation of WAe001-A-58 human embryonic stem cell line with inducible expression of the SARS-CoV-2 nucleocapsid proteinSARS-CoV-2 뉴클레오캡시드 단백질의 유도성 발현을 갖는 WAe001-A-58 인간 배아 줄기 세포주의 생성Article Published on 2021-05-012022-09-11 Journal: Stem cell research [Category] SARS, 치료법, [키워드] activate celebrex cell line cell types Comorbidities Comorbidity COVID-19 death discharged embryonic embryonic stem cell expression Generation hospitalized COVID-19 patient hospitalized COVID-19 patients Host karyotype morphology multiple organ multiple organs nucleocapsid nucleocapsid protein PGE prostaglandin prostaglandin E Protein SARS-CoV SARS-CoV-2 SARS-CoV-2 N protein stem cell suggested the SARS-CoV-2 Transcription transcriptionally transposon Treatment [DOI] 10.1016/j.scr.2021.102197 PMC 바로가기 [Article Type] Article
The Economic Impact of the SARS-COV-2 (COVID-19) Pandemic in SpainArticle Published on 2021-04-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] analyzed Anomaly association Bayesian Bayesian Structural Time Series calculated change changed consequence correlation country COVID-19 COVID-19 crisis COVID-19 pandemic cumulative dependent on economic impact Effect employment estimate European examined GDP Generation had more Health Impact incidence of COVID-19 pandemic performed Retrospective analysis Spain Spanish statistical Uncertainty were recorded [DOI] 10.3390/ijerph18094708 PMC 바로가기 [Article Type] Article
Vaccines After an Emergency Use Authorization (EUA): Modern Evidence Generation ApproachesCommentary Published on 2021-04-222022-10-29 Journal: Therapeutic innovation & regulatory science [Category] COVID-19, MERS, SARS, [키워드] approval authorization COVID19 Critical Emergency Evidence Generation highlight immune response knowledge mechanism Regulatory Trial Vaccine [DOI] 10.1007/s43441-021-00290-z PMC 바로가기 [Article Type] Commentary
The Avon Longitudinal Study of Parents and Children – A resource for COVID-19 research: Generation 2 questionnaire data capture May-July 2020Data Note Published on 2021-04-142022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] affected ALSPAC Bristol children Children of the 90s children’s health Cohort Contact Contact patterns coronavirus COVID-19 COVID-19 pandemic Cross-generation dataset enrolled Generation Health initial lockdown lockdown restriction longitudinal management mental health National offspring pandemic parent parental parents participant population-based cohort pregnant pregnant women Prospective questionnaire questionnaire data recruited released Research resource response Sociodemographic supported unique women [DOI] 10.12688/wellcomeopenres.16414.2 PMC 바로가기 [Article Type] Data Note
Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing고처리량 항바이러스 스크리닝 및 테스트를 위한 SARS-CoV-2 리포터 복제 생성423 Published on 2021-04-132022-09-10 Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 유전자 메커니즘, 치료제, [키워드] accelerate acute respiratory syndrome acute respiratory syndrome coronavirus adopted Antiviral Antiviral compound Antiviral compounds antivirals biology of SARS-CoV-2 biosafety level Biosafety Level 3 BSL-3 Cell culture cell line cell lines cells competent Compound construction coronavirus costly COVID-19 COVID-19 pandemic effective effort expand Generation Genome high-throughput antiviral screening highlight implementation in vivo Infectious virus inhibited inhibiting viral replication inhibitor investigator Laboratory lack level 3 limitations mechanism overcome platform producing progeny virions provide RdRP RdRp mutation RdRp mutations Replication replicon reporter Research respiratory SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Significance Significant significant differences this system Treatment urgency Viral viral replication virus virus replication [DOI] 10.1073/pnas.2025866118 PMC 바로가기 [Article Type] 423