Mediterranean Diet for the Prevention of Gestational Diabetes in the Covid-19 Era: Implications of Il-6 In DiabesityReview Published on 2021-01-262022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] acute respiratory syndrome antioxidant body mass index C reactive protein cardio-diabesity coronavirus coronavirus disease COVID-19 COVID-19 pandemic cytokine diabetes diet Enzymes Factor fatty acids Gain hemoglobin highlight hyperglycemia IL-6 IL-6 level immune response immune system immunopathological IMPROVE include Infection Inflammation inhibit insulin resistance mechanism microbiota Minerals modulate NF-κB pathway nutraceuticals omega-3 outcome oxidative stress plant foods Polyunsaturated Predictive Pregnancy prevention protective effect raised reducing rising risk SARS-CoV-2 serum viral infection vitamins weight [DOI] 10.3390/ijms22031213 PMC 바로가기 [Article Type] Review
Obesity and COVID-19: what makes obese host so vulnerable?Review Published on 2021-01-042022-10-30 Journal: Immunity & Ageing : I & A [Category] COVID-19, [키워드] Cancer cardiovascular diseases coronavirus COVID-19 COVID-19 infection death diabetes disease disease pathogenesis elderly patients greater Hospitalization Host hypertension increased risk independent infected case infected with COVID-19 Inflammation innate and adaptive immunity insulin resistance microenvironment Mild Mortality mortality rate no symptom Novel coronavirus obese obesity outcome pandemic Patient predict provide resulting risk risk factor severe disease severe symptom severity significantly higher the disease Type underlying condition unique [DOI] 10.1186/s12979-020-00212-x PMC 바로가기 [Article Type] Review
Determinants of Increased Fibrinogen in COVID-19 Patients With and Without Diabetes and Impaired Fasting Glucose당뇨병이 있거나 없는 COVID-19 환자 및 공복 혈당 장애 환자에서 증가된 피브리노겐의 결정 요인Article Published on 2021-01-012022-09-11 Journal: Clinical and applied thrombosis/hemostasis : offic [Category] 바이오마커, [키워드] analyzed C-reactive protein control group COVID-19 COVID-19 patient COVID-19 patients CRP demographic data determinant diabete diabetes died elevated Factor fasting fasting glucose ferritin ferritin levels fibrinogen Final Glucose glucose metabolism group Hospitalization hypercoagulability IL-6 IL-8 Impaired impaired fasting glucose Increased Inflammation insulin insulin resistance interleukin interleukin-6 involved IQR Laboratory results Linear regression medical history metabolism Multiple Multiple linear regression Necrosis normal range Patient positively correlated R 2 reduce Regulation Serum ferritin significantly increased Signs and symptoms Symptoms TG level TG levels TNF-α Triglyceride triglycerides Tumor tumor necrosis tumor necrosis factor tumor necrosis factor-α was impaired [DOI] 10.1177/1076029621996445 PMC 바로가기 [Article Type] Article
Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategiesReview Published on 2020-12-032022-10-31 Journal: Clinical and Translational Allergy [Category] COVID-19, [키워드] acting Activation Asia COVID-19 COVID-19 mortality COVID-19 severity Cytokine storm death rate death rates develop Endoplasmic reticulum endothelial damage Europe Foods gallate Genistein geographical area insulin resistance kinase lowest Lung injury mechanism Nrf2 Nutrients obesity pathway Prevalence quercetin Rapamycin receptor reduce Research resveratrol severity of COVID-19 significant effect Stress sulforaphane transcription factor TRPA1 Variation [DOI] 10.1186/s13601-020-00362-7 PMC 바로가기 [Article Type] Review
Factors leading to high morbidity and mortality of COVID-19 in patients with type 2 diabetesReview Published on 2020-12-012023-07-13 Journal: Journal of diabetes [Category] SARS, [키워드] COVID-19 Cytokine storm Diabetes Mellitus Inflammation insulin resistance Mortality 新冠肺炎 死亡率 炎症 糖尿病 细胞因子风暴 胰岛素抵抗. [DOI] 10.1111/1753-0407.13085 PMC 바로가기 [Article Type] Review
Metabolic impact of weight loss induced reduction of adipose ACE-2 – Potential implication in COVID-19 infections?Randomized Controlled Trial Published on 2020-12-012022-10-05 Journal: Metabolism: clinical and experimental [Category] SARS, 임상, [키워드] ACE-2 adipose Adipose tissue Affect age analyzed angiotensin BMI cell entry changes in characterized Clamp control group COVID-19 downregulation enzyme expression Glucose improvement insulin insulin resistance Insulin sensitivity Intervention ISI liver metabolic metabolism modulation mRNA expression not affected obesity Potential predicted preserved Randomized receptor reduction Regulation responsible SARS-CoV-2 sensitivity Skeletal muscle subject subjects tissue tissue metabolism Trial was measured was reduced weight weight loss [DOI] 10.1016/j.metabol.2020.154401 PMC 바로가기 [Article Type] Randomized Controlled Trial
Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury?Short communication Published on 2020-12-012022-10-05 Journal: Biochimie [Category] 치료제, [키워드] acute respiratory distress Antibiotics antiretroviral antiviral agent Bacterial contributed coronavirus disease COVID-19 COVID-19 patients cytochrome P450 Cytokine storm death disease drug Drug hepatotoxicity Drug-induced liver injury Enzymes Epidemic Factors Fatty liver fibrosis fungal healthy individual hepatotoxic higher risk Hospitalized Hypothesis induce insulin resistance lipid homeostasis liver main mechanism mechanism metabolic disease mitochondrial dysfunction multi-organ failure NASH non-infected obese COVID-19 patient obese COVID-19 patients obesity other disease oxidative stress participated Patient patients receive Remdesivir required risk severity steatohepatitis steatosis syndrome systemic inflammation treat [DOI] 10.1016/j.biochi.2020.08.018 [Article Type] Short communication
ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19Review Published on 2020-11-272023-07-12 Journal: Clinical Science (London, England : 1979) [Category] SARS, [키워드] angiotensin converting enzyme 2 insulin resistance muscle metabolism Skeletal muscle [DOI] 10.1042/CS20200486 PMC 바로가기 [Article Type] Review
A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2Article Published on 2020-11-182022-10-30 Journal: Molecules [Category] COVID-19, [키워드] addition Alter Ammonium baculovirus bind binding binding affinity Cancer COVID-19 Culture Dipeptidyl peptidase 4 Diseases domain DPP4 ELISA full-length spike protein Human human cell human DPP4 hydrophobic Inflammatory insect cell insect cells insulin resistance Interaction MERS MERS virus novel pharmacological target posttranslational modification procedure produced protease Protein protocol purification question RBD recombinant Recombinant protein SARS-CoV-2 SARS-CoV-2 spike protein Spike protein steatosis surface receptor the SARS-CoV-2 the spike protein therapy type 2 diabete understanding virus were measured [DOI] 10.3390/molecules25225392 PMC 바로가기 [Article Type] Article
An Immediate and Long-Term Complication of COVID-19 May Be Type 2 Diabetes Mellitus: The Central Role of β-Cell Dysfunction, Apoptosis and Exploration of Possible MechanismsReview Published on 2020-11-132022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] β-cell apoptosis accelerate accelerated ACE2 acute respiratory syndrome advanced age amylin Apoptosis blood glucose caused cellular co-morbidity Complication complications Coronavirus-2 COVID-19 develop disease dysfunction elevated exploration fibrosis Gender Glucose help hypertension Immediate Inflammation Injury insulin resistance islet islet amyloid male metabolic syndrome Microscopy novel coronavirus disease obesity observation oxidative stress pancreatic pandemic renin–angiotensin–aldosterone-system responsible role SARS-CoV-2 severity of COVID-19 Stress syndrome the WHO tissue tissues Type type 2 diabete [DOI] 10.3390/cells9112475 PMC 바로가기 [Article Type] Review