Severe patient – Page 9 – Communicable Diseases Research

A systematic meta-analysis of immune signatures in patients with COVID-19

COVID-19 환자의 면역 신호에 대한 체계적인 메타 분석

Meta-Analysis

Published on 2021-07-012022-09-12
Journal: Reviews in Medical Virology [Category] SARS, 진단,

Lymphocyte subset alterations with disease severity, imaging manifestation, and delayed hospitalization in COVID-19 patients

Research Article

Published on 2021-07-012022-10-28
Journal: BMC Infectious Diseases [Category] COVID-19, SARS,

Analysis of the Impact of the Coronavirus Disease Epidemic on the Emergency Medical System in South Korea Using the Korean Triage and Acuity Scale

Observational Study

Published on 2021-07-012022-10-05
Journal: Yonsei medical journal [Category] SARS, 임상,

Proteome Profiling of Recombinant DNase Therapy in Reducing NETs and Aiding Recovery in COVID-19 Patients

Research

Published on 2021-06-152022-10-30
Journal: Molecular & Cellular Proteomics : MCP [Category] COVID-19,

[키워드] Abstract accumulation acute respiratory distress Adverse reaction AF, Alexa Fluor airway airways analyses Analysis approved ARDS, acute respiratory distress syndrome blood plasma CF, cystic fibrosis change clinically components contribute coronavirus disease COT, conventional oxygen therapy COVID-19 COVID-19 disease COVID-19, Coronavirus disease 2019 DAPI, 4,6 diamidino-2-phenylindole DIA-MS, data-independent acquisition MS DNA DNase ECMO, extracorporeal membrane oxygen therapy extracellular DNA FDR, false discovery rate FiO₂, fraction of inspired oxygen FIVE GGO, glass ground opacity hallmark hemorrhage HFNO, high-flow nasal oxygenation high-flow oxygen therapy hindrance Hypoxemia immunofluorescence implication IMPROVE infections Inflammation iRT, indexed retention time peptides Lung function mass spectrometry Microscopy NE, neutrophil elastase NET NET, neutrophil extracellular trap NETs Neutrophil extracellular trap oxygen saturation Oxygenation PADI-4, peptidyl arginine deiminase IV Patient patients plasma Pneumonia Profiling proteome pulmonary inflammation Quantitative recombinant reduce reduced reducing reduction Respiratory failure rhDNase, recombinant human DNase I Roche SARS-CoV2, severe acute respiratory syndrome coronavirus 2 severe COVID-19 patient severe COVID-19 patients Severe patient severely ill patient shown SpO₂, the oxygen saturation as measured by pulse oximetry sputum statistically significant Symptom syndrome systemic inflammatory targeting the disease therapeutic therapy treated Treatment with COVID-19
[DOI] 10.1016/j.mcpro.2021.100113 PMC 바로가기 [Article Type] Research

The TNFRSF13C H159Y Variant Is Associated with Severe COVID-19: A Retrospective Study of 500 Patients from Southern Italy

TNFRSF13C H159Y 변이체는 심각한 COVID-19와 관련이 있습니다: 남부 이탈리아에서 온 500명의 환자에 대한 후향적 연구

Communication

Published on 2021-06-082022-09-10
Journal: Genes [Category] MERS, 변종, 유전자 메커니즘,

[키워드] Activation allele analyzed asymptomatic subject B-cell build coding sequence coding sequences contribute COVID-19 CVID disease severity examined genetic determinant genetic determinants genetic risk factor genotyped hospitalized patients Host Humoral immunity identify immunodeficiency involved Italy management mechanism NF-kB non-severe patient pathogenic Point mutation positive predicted rationale risk SARS-CoV-2 Severe case severe COVID-19 Severe patient severe patients severity significant enrichment significantly more SNP genotyping subject the disease therapy TNFRSF13C variant whole-exome sequencing
[DOI] 10.3390/genes12060881 PMC 바로가기 [Article Type] Communication

Successful Treatment of a Critically Ill COVID-19 Patient Using Continuous Renal Replacement Therapy With Enhanced Cytokine Removal and Tocilizumab: A Case Report

Medicine

Published on 2021-06-072022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] Acute kidney injury anti-cytokine therapy biochemical caused Comprehensive Continuous Continuous renal replacement therapy Course COVID-19 COVID-19 pandemic COVID-19 patient Critically ill Critically ill patient CRS cytokine Cytokine release syndrome death Disease activity enhanced extracorporeal membrane oxygenation hemodynamic Hemoperfusion high mortality highlight Ill immune modulation Intervention mechanical ventilation multi-organ failure Oxygenation parameters Patient predicted provided removal replacement report required Respiratory failure risk severe COVID-19 Severe patient Support sustained therapy Tocilizumab treat Treatment uremic with COVID-19
[DOI] 10.3389/fmed.2021.649583 PMC 바로가기 [Article Type] Medicine

Machine learning predictive model for severe COVID-19

심각한 COVID-19에 대한 머신 러닝 예측 모델

Article

Published on 2021-06-012022-09-11
Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 바이오마커, 유전자 메커니즘,

Dynamic changes in coagulation parameters and correlation with disease severity and mortality in patients with COVID-19

Research Paper

Published on 2021-05-312022-10-28
Journal: Aging (Albany NY) [Category] COVID-19, SARS,

Transcriptional Start Site Coverage Analysis in Plasma Cell-Free DNA Reveals Disease Severity and Tissue Specificity of COVID-19 Patients

Genetics

Published on 2021-05-282022-10-31
Journal: Frontiers in Genetics [Category] COVID-19,

[키워드] acute respiratory distress affected Analysis antiviral activity Asymptomatic biological processe Biomarker blood cell Blood cells cell-free DNA cfDNA Characteristics Clinical management control group coronavirus disease Coverage COVID-19 COVID-19 patients COVID-19 progression COVID-19 severity critical condition Cytokine storm death demonstrated disease severity DNA downregulated gene evidenced feasibility function Gene Expression high risk immune system individual Infection involved lung cell lung cells mechanism noninvasive plasma plasma DNA provided Region SARS-CoV-2 Severe case severe COVID-19 patient severe COVID-19 symptoms Severe patient severe patients severe pneumonia Site the disease tissue tissue specificity transcriptional Transcriptome TSS coverage upregulated gene utility Variation viral replication
[DOI] 10.3389/fgene.2021.663098 PMC 바로가기 [Article Type] Genetics

Association of Clinical and Immunological Characteristics With Disease Severity and Outcomes in 211 Patients With COVID-19 in Wuhan, China

Cellular and Infection Microbiology

Published on 2021-05-282022-10-31
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS,

[키워드] Admission age Analysis B cells body temperature CD4+ T cells CD8+ T cell changes in clinical Clinical characteristics Clinical outcome clinician Comorbidities Comorbidity Coronavirus disease 2019 COVID-19 COVID-19 patients CREA creatinine Critical disease deterioration Disease progression disease severity duration of fever effective intervention expression feature functions global public health higher risk Hospital stay identify IL-6 immunological immunological characteristics indicated information Laboratory liver Logistic lymphocyte lymphocyte counts lymphopenia Male sex median age non-severe cases non-severe patient non-severe patients Older age Patient patients with COVID-19 peripheral lymphocyte predominant presenting progression recruited renal Result risk risk factor selective serum Serum level Severe case severe cases Severe patient severe patients significantly subpopulations subset sustained fever Symptom university WBC White blood cell with COVID-19 Wuhan Wuhan, China
[DOI] 10.3389/fcimb.2021.667487 PMC 바로가기 [Article Type] Cellular and Infection Microbiology