Before the 2020 Pandemic: an observational study exploring public knowledge, attitudes, plans, and preferences towards death and end of life care in WalesResearch Article Published on 2021-07-202022-10-27 Journal: BMC Palliative Care [Category] Coronavirus, SARS, [키워드] advance analysed approach being Care Combination communication conducted COVID-19 Cultural issues death Death and dying End end of life care Health information inhibited knowledge lack less life Loss media participant Participants participated Planning platform positive preference preferences professional public attitudes public health Quality of life recruit Result social media standard procedure supplementary material Support supportive care Terminal care thematic analysis understanding were used [DOI] 10.1186/s12904-021-00806-2 PMC 바로가기 [Article Type] Research Article
Improving Outcomes of Chemotherapy: Established and Novel Options for Myeloprotection in the COVID-19 EraOncology Published on 2021-07-082022-10-31 Journal: Frontiers in Oncology [Category] COVID-19, [키워드] Administered Affect Anemia approved Blood Cell Chemotherapy clinical development COVID-19 COVID-19 pandemic decrease dose growth factor Health health systems Hospitalization hospitalizations Improving incidence inhibitor Intervention intravenous less lung cancer maintain management myeloprotection myelosuppression neutropenia novel option Patient patients patients receiving placebo patients treated Physicians placebo-controlled clinical study progenitor cell Quality of life receiving recommendation reduced reducing regimen risk of infection Side effect significantly Standard-of-care supportive care thrombocytopenia Treatment [DOI] 10.3389/fonc.2021.697908 PMC 바로가기 [Article Type] Oncology
Cardiac manifestations of the coronavirus disease-19: a review of pathogenesis, clinical manifestations, diagnosis, and treatment코로나 바이러스 질병의 심장 증상 -19 : 병인, 임상 증상, 진단 및 치료의 검토Review Published on 2021-07-062022-09-10 Journal: The Pan African Medical Journal [Category] MERS, SARS, 바이오마커, [키워드] Acute kidney injury acute respiratory distress acute respiratory distress syndrome AKI Anti-viral therapy approach ARDS best Biomarker cardiac cardiac complication Cardiac complications Cardiomyopathies cardiovascular cardiovascular disease caused Chest chest pain chest tightness clinical manifestations coronavirus coronavirus disease Coronavirus disease-19 COVID-19 COVID-19 patient CVD D-dimer Diagnosis dimer disease drugs ECG Effective strategies effective strategy electrocardiogram fibrinogen healthcare worker heart failure hemodynamic Hemodynamic monitoring IL-6 IL-6 blockers Inflammatory marker inflammatory markers Liver damage manifestation manifested morbidity and mortality myocarditis N-terminal NT-proBNP pandemic Pathogenesis peptide performed Pneumonia pro-B-type natriuretic peptide reduce Research respiratory respiratory distress SARS-CoV-2 Septic shock Severe acute respiratory syndrome severe cases statins supportive care syndrome telemetry thrombolytic tissue Treatment troponin Wuhan Wuhan, China [DOI] 10.11604/pamj.2021.39.173.27802 PMC 바로가기 [Article Type] Review
Hormonal intervention for the treatment of veterans with COVID-19 requiring hospitalization (HITCH): a multicenter, phase 2 randomized controlled trial of best supportive care vs best supportive care plus degarelix: study protocol for a randomized controlled trial입원이 필요한 COVID-19 참전 용사 치료를 위한 호르몬 개입(HITCH): 최상의 지지 요법 대 최상의 지지 요법과 데가렐릭스의 다기관, 2상 무작위 대조 시험: 무작위 대조 시험을 위한 연구 프로토콜Study Protocol Published on 2021-07-052022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] addition age Analysis androgen Androgen receptor Androgen suppression Anti-androgen anti-viral antibody approved association best Cell Chain Reaction Clinical improvement Clinical outcome clinical outcomes clinical trial Comorbidity coronavirus COVID-19 COVID-19 illness COVID-19 infection COVID-19 severity Cytokines degarelix determine double-blind Efficacy Exploratory analyses expression Factor FDA Hormone therapy Hospitalization Hospitalized host cell host cell surface Human hypertension IMPROVE include infection with SARS-CoV-2 Intervention Invasive mechanical ventilation investigated LHRH lung epithelium Luteinizing Hormone male mechanical ventilation Mortality multicenter Nasopharyngeal swab normal temperature outcome Patient patients hospitalized performed Phase 2 Placebo placebo-controlled polymerase chain polymerase chain reaction positive positive reverse transcriptase polymerase chain reaction primary endpoint Prostate cancer protease randomization Randomized Randomized controlled trial receptor signaling reduce required reverse transcriptase SARS-CoV-2 SARS-CoV-2 cell SARS-CoV-2 entry secondary endpoint severity severity of COVID-19 severity of illness single dose stratified Study protocol supportive care suppress symptom severity target tissue temperature therapeutic targeting therapy TMPRSS2 TMPRSS2 expression transcriptase Treatment Trial Trial registration veteran Viral Viral load with COVID-19 [DOI] 10.1186/s13063-021-05389-0 PMC 바로가기 [Article Type] Study Protocol
The effect of propolis plus Hyoscyamus niger L. methanolic extract on clinical symptoms in patients with acute respiratory syndrome suspected to COVID-19: A clinical trialCOVID-19로 의심되는 급성 호흡기 증후군 환자의 임상 증상에 대한 프로 폴리스 + 하이시 아미스 니제르 L. 메탄올 추출물의 효과 : 임상 시험Randomized Controlled Trial Published on 2021-07-012022-08-31 Journal: Phytotherapy research : PTR [Category] 임상, 치료제, [키워드] abdominal pain acute respiratory syndrome Administered administration Antiviral treatment caused chest pain clinical symptom Clinical symptoms clinical trial conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease diarrhea disease Dizziness dry cough Effect effective evaluate the effect Fever groups headache Health Health crisis Hyoscyamus niger Hyoscyamus niger L. Intervention Iran Medical Sciences nausea nausea and vomiting not effective outbreak Patient patients with COVID-19 Placebo placebo group Propolis randomized clinical trial reduced referred to Shortness of breath Signs and symptoms sore throat supportive care symptomatic symptoms of COVID-19 syrup the placebo group treating COVID-19 Treatment two group two groups vomiting [DOI] 10.1002/ptr.7116 PMC 바로가기 [Article Type] Randomized Controlled Trial
Health and social care professionals’ experiences of providing end of life care during the COVID-19 pandemic: A qualitative studyOriginal Articles Published on 2021-07-012022-10-29 Journal: Palliative medicine [Category] Coronavirus, SARS, [키워드] analysed approach Care Clinical practice clinical setting connection Contact COVID-19 COVID-19 pandemic creating death dying patient emotional End of life experience facilitator Final First wave flexible Health healthcare professionals help impacted increases in Palliative care pandemic participant Patient platform professional promote psychosocial wellbeing qualitative study reduced reported Result social care professionals Support supportive care thematic analysis United Kingdom [DOI] 10.1177/02692163211017808 PMC 바로가기 [Article Type] Original Articles
The most important biomarker associated with coagulation and inflammation among COVID-19 patientsCOVID-19 환자에서 응고 및 염증과 관련된 가장 중요한 바이오마커Review Published on 2021-07-012022-09-11 Journal: Molecular and cellular biochemistry [Category] 바이오마커, 치료제, [키워드] Abnormalities abnormality acute lung injury Biomarker caused Coagulation coagulation test Coagulopathy Complication conditions coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patient COVID-19 patients Critical CRP D-dimer Disseminated intravascular coagulopathy early stage early stages elevated ferritin fibrinogen fibrinogen degradation products fibrinogen level Fibrinogen levels IL-6 Immunity Infection Inflammation inflammatory biomarkers inflammatory change inflammatory changes initial lack LDH leads Lung injury Lungs management multiorgan failure occur organ partial thromboplastin time Patient patients patients worldwide Platelet Platelet count Prophylaxis prothrombin Prothrombin time Respiratory failure severe patients significantly suggested supportive care target organ Test screening the disease thromboembolic THROMBOPLASTIN Viral virus [DOI] 10.1007/s11010-021-04122-4 PMC 바로가기 [Article Type] Review
Effectiveness and safety of favipiravir compared to supportive care in moderately to critically ill COVID-19 patients: a retrospective study with propensity score matching sensitivity analysis중등도에서 중증 COVID-19 환자의 지지 요법과 비교한 favipiravir의 효과 및 안전성: 성향 점수 일치 민감도 분석을 사용한 후향적 연구Article Published on 2021-07-012022-09-11 Journal: Current medical research and opinion [Category] Coronavirus, SARS, 치료제, [키워드] 95%CI accelerated adjusted Analysis benefit Chain Reaction clinical benefits conducted Coronavirus 2019 COVID-19 COVID-19 patients Critical Critically ill diagnosed discharge discharge rate Effectiveness Favipiravir followed by hospital independent risk factor Kaplan-Meier lack less Loading dose mechanical ventilation mechanically ventilated patients median time Mild Mortality Nasopharyngeal swab no significant effect outcome overall mortality Patient performed polymerase chain polymerase chain reaction progression Propensity score propensity score matching PSM real-time polymerase chain reaction real-world data retrospective Retrospective study RT-PCR SARS-CoV-2 Saudi Arabia sensitivity analysis severity statistically study period supportive care the disease treat Treatment Trial were excluded were used WHO criteria [DOI] 10.1080/03007995.2021.1920900 PMC 바로가기 [Article Type] Article
Multisystem inflammatory syndrome in adults: A rare sequela of SARS-CoV-2 infection성인의 다기관 염증 증후군: SARS-CoV-2 감염의 드문 후유증Case Reports Published on 2021-07-012022-09-12 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, [키워드] Aggressive CDC center children Clinical course clinical recovery Control COVID-19 heart failure High-dose immunomodulatory Inflammatory initial intensive care Intravenous immunoglobulin MIS-C Multisystem inflammatory syndrome in adults (MIS-A) Patient predictors prevention Research SARS-COV-2 infection Steroids supportive care syndrome the disease the patient the United State Topic Treatment [DOI] 10.1016/j.ijid.2021.05.050 PMC 바로가기 [Article Type] Case Reports
Tofacitinib as an Adjunct Immunomodulator for Treatment of a Patient with Severe COVID-19: A Case ReportCase Report Published on 2021-06-302022-10-30 Journal: JNMA: Journal of the Nepal Medical Association [Category] Coronavirus, SARS, [키워드] dexamethasone immunomodulation addition adjunct coronavirus disease COVID-19 Dexamethasone immunomodulator IMPROVE janus Kinase inhibitor outcome Patient patients progressive respiratory failure proportion report Respiratory Support Serum inflammatory biomarkers shown steroid supportive care Tofacitinib use of corticosteroid use of steroids worsening [DOI] 10.31729/jnma.6680 PMC 바로가기 [Article Type] Case Report