AMP-activated protein kinase
[용어속성] Term
The favorable impacts of silibinin polyphenols as adjunctive therapy in reducing the complications of COVID-19: A review of research evidence and underlying mechanisms
Review article
Published on
Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료제,
Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료제,
[키워드] ACE2angiotensin converting enzyme
AMP-activated protein kinase
AMPKAMP-activated protein kinase
angiotensin converting enzyme
antigen-presenting cells
antioxidant
APCantigen-presenting cells
c‐Jun N‐terminal kinase
clinical trial
Complication
coronavirus disease
Coronavirus disease 2019
COVID-19
COVID-19coronavirus disease 2019
database
Direct
Diseases
distress
Effect
ERKextracellular signal-regulated kinase
Evidence
exhibited
extracellular signal-regulated kinase
Factor
HBVHepatitis B virus
HCVHepatitis C virus
Hepatitis B virus
hepatitis C virus
HIVhuman immunodeficiency virus
Human immunodeficiency virus
IFNγinterferon γ
ILInterleukin
immune system
Immune system dysfunction
Impact
indicate
Inflammation
Inflammatory response
interferon γ
interleukin
involved
JAKc‐Jun N‐terminal kinase
Like
MAPKmitogen-activated protein kinase
mechanism
MERS-CoVmiddle east respiratory syndrome coronavirus
Middle East respiratory syndrome Coronavirus
mitogen-activated protein kinase
neutrophil-lymphocyte-ratio
NF-κBnuclear factor kappa B
nitric oxide
NLRneutrophil-lymphocyte-ratio
NONitric Oxide
Nrf2nuclear factor erythroid 2–related factor 2
nuclear factor erythroid 2–related factor 2
nuclear factor kappa B
oxidative stress
pandemic
pathogenesis of COVID-19
protease
reactive oxygen species
reducing
Research
ROSreactive oxygen species
SARS-CoV 2severe acute respiratory syndrome coronavirus
SARS-CoV-2
SARSSevere Acute Respiratory Syndrome
Science
searched
Severe acute respiratory syndrome
severe acute respiratory syndrome Coronavirus
signal transducer and activation of transcription
silibinin
spike glycoprotein
STATsignal transducer and activation of transcription
T helper 1
target protein
TGF-βtransforming growth factor beta
Th1T helper 1
therapeutic benefits
therapeutic effect
therapy
TLR-4toll like receptor 4
toll like receptor 4
transforming growth factor beta
treating COVID-19
viral replication
Web of Science
WHOWorld Health Organization
World Health Organization
[DOI] 10.1016/j.biopha.2022.113593 [Article Type] Review article
[DOI] 10.1016/j.biopha.2022.113593 [Article Type] Review article
Role of senescence in the chronic health consequences of COVID-19
Review article
[키워드] A phase 2 placebo-controlled pilot study in COVID-19 of Fisetin to Alleviate Dysfunction and Excessive Inflammatory Response in Older Adults in Nursing Homes
acute COVID-19
alleviate
alterations
AMP-activated protein kinase
AMPKAMP-activated protein kinase
caloric restriction
Cell
cell removal
cellular senescence
chronic disease
consequence
contribute
Coronavirus disease 2019
COVID-19
COVID-19 symptom
COVID-19coronavirus disease 2019
COVID-FISA phase 2 placebo-controlled pilot study in COVID-19 of Fisetin to Alleviate Dysfunction and Excessive Inflammatory Response in Older Adults in Nursing Homes
CRcaloric restriction
Defense
deregulated
dysfunction
Epigenetic
facility for geroscience analysis
FGAFacility for Geroscience Analysis
generate
genomic
greater
Health
ICUIntensive Care Unit
IFintermittent fasting
ill patients
Immune system dysfunction
increased risk
indicated
Infection
infections
Innate
intensive care unit
Intercellular communication
interfere
intermittent fasting
Intervention
Long-term care facility
low-grade inflammation
LTCFlong-term care facility
mammalian target of rapamycin
MCCmultiple chronic conditions
MERS-CoVmiddle east respiratory syndrome coronavirus
Middle East respiratory syndrome Coronavirus
mitochondrial dysfunction
Mortality
mTORmammalian target of rapamycin
Multimorbidity
multiple chronic conditions
NAD+nicotinamide adenine dinucleotide
nicotinamide adenine dinucleotide
nicotinamide mononucleotide
nicotinamide riboside
NMNnicotinamide mononucleotide
NRnicotinamide riboside
Older
outcome
PACSpostacute sequalae of SARS-CoV-2 infection
PAMPspathogen-associated molecular profile factors
pathogen-associated molecular profile factors
Patient
postacute sequalae of SARS-CoV-2 infection
predictor
reactive oxygen species
risk
risk factor
role
ROSreactive oxygen species
SARS-CoV-1severe acute respiratory syndrome coronavirus 1
SARS-COV-2 infection
SARS-CoV-2severe acute respiratory syndrome coronavirus 2
SARSSevere Acute Respiratory Syndrome
SASPsenescence-associated secretory phenotype
senescence-associated secretory phenotype
senescent
senescent cell
Severe acute respiratory syndrome
severe acute respiratory syndrome coronavirus 1
severe acute respiratory syndrome coronavirus 2
skilled nursing facility
SNFskilled nursing facility
susceptibility
TGNtranslational geroscience network
Translational Geroscience Network
viral infection
viral infections
while
WHOWorld Health Organization
World Health Organization
[DOI] 10.1016/j.trsl.2021.10.003 [Article Type] Review article
[DOI] 10.1016/j.trsl.2021.10.003 [Article Type] Review article