Obesity and clinical outcomes in COVID-19 patients without comorbidities, a post-hoc analysis from ORCHID trialClinical Trial Published on 2022-07-292022-10-04 Journal: Frontiers in Endocrinology [Category] 임상, [키워드] 95% CI adjusted Analysis BMI Clinical outcome Comorbidities Comorbidity COVID-19 COVID-19 in patient COVID-19 patient Cox regression Cox regression analysis death deaths defined described died discharge Effect Evidence hazard ratio hospital hospitalized COVID-19 patient individual Inpatient multivariate obese obesity occurred post-hoc analysis Prognosis Prospective trial required significantly Trial was used with COVID-19 worse prognosis [DOI] 10.3389/fendo.2022.936976 PMC 바로가기 [Article Type] Clinical Trial
Inactivated Whole-virus Vaccine Triggers Low Response Against SARS-CoV-2 Infection Among Renal Transplant Patients: Prospective Phase 4 Study Results비활성화된 전체 바이러스 백신은 신장 이식 환자에서 SARS-CoV-2 감염에 대한 낮은 반응을 유발합니다: 예상 4상 연구 결과Clinical Trial Published on 2022-04-012022-09-11 Journal: Transplantation [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, [키워드] A significant reduction acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adverse reaction Adverse reactions Against Analysis antibody Antibody Response Antibody responses clinical effectiveness Cohort CoronaVac coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death elicit first dose humoral Humoral response IgG antibodies IgG antibody inactivated incidence of COVID-19 increase individual intramuscular dose kidney transplant recipients lack lethality rate lethality rates mRNA vaccine Neutralizing antibodies occurred Patient patients phase 4 proportion Prospective Prospective trial reactogenicity recipient recipients reduced reduction in remained reported respiratory response Result SARS-CoV-2 second dose Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus single-center solid-organ transplant Transplant transplantation Trigger vaccination vaccination schedule Vaccine [DOI] 10.1097/TP.0000000000004036 PMC 바로가기 [Article Type] Clinical Trial
Testing the feasibility of operationalizing a prospective, randomized trial with remote cardiac safety EKG monitoring during a pandemicRandomized Controlled Trial Published on 2022-03-012022-10-05 Journal: Journal of interventional cardiac electrophysiology : an international [Category] SARS, 임상, [키워드] approval approved cardiac toxicity changes in clinical clinical trial Contact contagious coronavirus SARS-CoV-2 COVID COVID-19 death dose ECG EKG EKG monitoring Emergency use evaluate Evidence FDA feasibility feasible Follow-up form HCQ home hospitalizations household contact Hydroxychloroquine in vitro activity initiated investigator observation pandemic participant Participants Patient PCR test physical contact positive Prophylaxis Prospective Prospective trial QTC prolongation Randomized randomized trial recorded remote Saliva Sample size SARS-CoV-2 symptomatic Testing Trial [DOI] 10.1007/s10840-021-00989-x PMC 바로가기 [Article Type] Randomized Controlled Trial
Complement system component dysregulation is a distinctive feature of COVID-19 disease: a prospective and comparative analysis of patients admitted to the emergency department for suspected COVID-19 diseaseClinical Trial Published on 2021-12-142022-10-04 Journal: Journal of Thrombosis and Thrombolysis [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] activated Activation acute respiratory syndrome Analysis Antigen automated both groups C5a calprotectin classical pathway clinical Coagulopathy Cohort complement complement components complement system component control group coronavirus Coronavirus disease 2019 correlation COVID-19 COVID-19 disease COVID-19 infection COVID-19 patient COVID-19 patients Data analysis diagnosis of COVID-19 dysregulation emergency department Laboratory lateral flow Level no difference pathophysiology Patient plasma positive Prospective trial Quantitative SARS-CoV-2 serum significantly higher supplementary material tested Vascular damage von Willebrand factor was determined were assessed were measured with COVID-19 [DOI] 10.1007/s11239-021-02617-x PMC 바로가기 [Article Type] Clinical Trial
Whole-lung low-dose radiation therapy (LD-RT) for non-intubated oxygen-dependent patients with COVID-19-related pneumonia receiving dexamethasone and/or remdesevir덱사메타손 및/또는 렘데세비르를 투여받는 COVID-19 관련 폐렴이 있는 삽관되지 않은 산소 의존 환자를 위한 전폐 저선량 방사선 요법(LD-RT)Article Published on 2021-12-012022-09-11 Journal: Radiotherapy and oncology : journal of the Europea [Category] SARS, 바이오마커, 비임상, 치료기술, [키워드] Adding addition Analysis animal model anti-inflammatory effect Anti-inflammatory effects Biomarkers biomarkers of inflammation breath C-reactive protein cardiac injury clinical clinical recovery Cohort Control controls COVID-19 COVID-19 patient creatine creatine kinase CRP declined Dexamethasone drug therapy drug treatment drug treatments febrile Hospitalization Inflammation Injury intubation Intubation rates low-dose Low-dose radiation Non-intubated outcome oxygen Oxygenation Patient patients evaluated Pneumonia predicted Predictive produced Prospective trial radiation therapy Radiographic Radiotherapy randomized trial receiving reduced reduction reduction in Significant significant differences subset survival therapy treated Treatment Trial [DOI] 10.1016/j.radonc.2021.10.003 PMC 바로가기 [Article Type] Article
1602P COVID-19 vaccination efficacy in cancer patients: An ongoing prospective trialConference abstract Published on 2021-09-012022-10-05 Journal: Annals of oncology : official journal of the Europ [Category] 유전자 메커니즘, [키워드] Cancer COVID-19 vaccination Efficacy Prospective trial [DOI] 10.1016/j.annonc.2021.08.1595 [Article Type] Conference abstract
Could pulmonary low-dose radiation therapy be an alternative treatment for patients with COVID-19 pneumonia? Preliminary results of a multicenter SEOR-GICOR nonrandomized prospective trial (IPACOVID trial)폐 저용량 방사선 요법이 COVID-19 폐렴 환자에게 대안 치료가 될 수 있습니까?다기관 지구-지정기 비 랜덤 화 전망 시험의 예비 결과 (Ipacovid 시험)Clinical Trial Published on 2021-07-062022-08-13 Journal: Strahlentherapie Und Onkologie [Category] MERS, SARS, 임상, [키워드] Admission adverse effect adverse effects age Anti-inflammatory effects appear arterial oxygen partial pressure bilateral pulmonary infiltrate bilateral pulmonary infiltrates candidate Chest Comorbidities Comorbidity coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia criteria CT scan Dexamethasone dose Efficacy and safety Endpoint enrolled evaluate evaluated fractional inspired oxygen Hospitalization intensive care intensive care unit interstitial pneumonia irradiation low-dose Low-dose radiation therapy lung lung involvement Lung irradiation material men multicenter nonrandomized oxygen oxygen partial pressure PaO parameter partial pressure Patient patients with COVID-19 Pneumonia primary endpoint Prospective trial pulse oximetry Radiation radiation therapy radiation treatment reported respiratory Result Safe supplementary material systemic inflammatory those who survived Treatment Treatment outcome Trial was increased with COVID-19 women [DOI] 10.1007/s00066-021-01803-3 PMC 바로가기 [Article Type] Clinical Trial
Acute kidney injury in COVID-19: are kidneys the target or just collateral damage? A comprehensive assessment of viral RNA and AKI rate in patients with COVID-19COVID-19의 급성 신장 손상: 신장이 표적입니까 아니면 부수적인 손상입니까? COVID-19 환자의 바이러스 RNA 및 AKI 비율에 대한 포괄적인 평가Review Published on 2021-07-012022-09-11 Journal: Current opinion in urology [Category] SARS, 치료기술, 치료제, [키워드] Acute kidney injury acute respiratory syndrome AKI available data causative agent Chronic kidney disease CKD confidence interval coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 severity Cytokine storm detect Effect Frequency identify in urine kidney Kidney disease Kidney function Kidney injury moment MOST mRNA Odds ratio Patient patients with COVID-19 Prospective trial recent Research Ribonucleic acid RNA SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome-related coronavirus severity the disease the patient Topic undetectable Urine viral ribonucleic acid Viral RNA [DOI] 10.1097/MOU.0000000000000901 PMC 바로가기 [Article Type] Review
Quantitative assessment of SARS-CoV-2 RNAemia and outcome in patients with coronavirus disease 2019SARS-CoV-2 RNA혈증의 정량적 평가 및 코로나바이러스 질환 환자의 결과 2019Meta-Analysis Published on 2021-05-012022-09-11 Journal: Journal of medical virology [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition Admission association asymptomatic infection Blood Clinical outcome clinical outcomes Clinical practice Clinical severity conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 severity Critical Critical illness death death in COVID-19 disease severity Disease spectrum ICU ICU admission identification intensive care intensive care unit Invasive mechanical ventilation Meta-analysis Mortality multiple organ failure Odds ratio outcome Patient Prevalence prognostic indicator Prognostic marker Prognostic markers progression Prospective trial random-effects model risk factor RNA SARS-CoV-2 SARS-CoV-2 RNAaemia severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity unfavorable outcome. with COVID-19 [DOI] 10.1002/jmv.26876 PMC 바로가기 [Article Type] Meta-Analysis
Efficacy of the combination of modern medicine and traditional Chinese medicine in pulmonary fibrosis arising as a sequelae in convalescent COVID-19 patients: a randomized multicenter trial회복기 COVID-19 환자의 후유증으로 발생하는 폐 섬유증에 대한 현대 의학 및 한약 조합의 효능: 무작위 다기관 시험Clinical Trial Published on 2021-03-182022-09-10 Journal: Infectious Diseases of Poverty [Category] SARS, 임상, 치료제, [키워드] (pirfenidone acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Administered affected affecting age arising candidate caused Chinese Chinese Clinical Trial Registry clinical clinical manifestation clinical manifestations Combination conducted control group control groups convalescent coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 cases Critical critical condition deficiency determine Effectiveness eligible expiratory expiratory vital capacity feasible fibrosis IMPROVE Inclusion indicated infected patient infected patients lead life Lung function manifestation modern medicine mortalities Mortality multicenter Multicenter trial parallel-group participant Patient patients Pirfenidone Placebo Prospective clinical trial Prospective trial Psychology pulmonary pulmonary fibrosis Quality of life Randomized receive recorded reducing Registered registry reported respiratory SARS-CoV-2 SARS-COV-2 infection SASR-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 significantly syndrome TCM the disease Traditional Chinese medicine Treatment treatment group Trial registration two groups vital capacity Well-being [DOI] 10.1186/s40249-021-00813-8 PMC 바로가기 [Article Type] Clinical Trial