The effect of cardiovascular disease and acute cardiac injury on fatal COVID-19: a meta-analysisReview article Published on 2021-10-012022-10-05 Journal: The American journal of emergency medicine [Category] 바이오마커, [키워드] 95% CI Acute cardiac injury Biomarker cardiac injury cardiovascular disease cardiovascular diseases country COVID-19 COVID-19 pandemic CVD database evaluate higher risk Hospital stay hospitalized COVID-19 patient hospitalized COVID-19 patients increase in Injury Laboratory Meta analysis Meta-analysis Mortality mortality risk non-survivor objective outcome performed Population Prevalence reached Result risk factor Separate severe COVID-19 significantly higher subgroup suggested survivor systematic literature search was performed [DOI] 10.1016/j.ajem.2021.04.013 [Article Type] Review article
Dynamics in Anemia Development and Dysregulation of Iron Homeostasis in Hospitalized Patients with COVID-19Article Published on 2021-09-252022-10-30 Journal: Metabolites [Category] COVID-19, [키워드] Admission analyzed Anemia anemia of inflammation Clinical course Concentration COVID-19 COVID-19 patient decrease development died discharge disease severity driven by Dynamics dysregulated ferritin hemoglobin hemoglobin course higher risk hospital Hospital stay Hospitalization Hospitalized hospitalized COVID-19 patients hyperinflammation ICU admission In-hospital death increased risk Infection Inflammation iron iron deficiency iron homeostasis median metabolism Mortality normalized outcome Patient patients patients with COVID-19 Prevalence recovery risk factor SARS-CoV-2 severe disease still hospitalized subject Transferrin university with COVID-19 [DOI] 10.3390/metabo11100653 PMC 바로가기 [Article Type] Article
High-value laboratory testing for hospitalized COVID-19 patients: a reviewReview Published on 2021-09-212022-10-31 Journal: Future Virology [Category] COVID-19, [키워드] Absolute lymphocyte count Abstract Admission AST Bacterial Biomarker Blood Blood clots Blood coagulation Cardiac complications cardiac troponin Care clinician Co-infection complex complications of COVID-19 Course COVID-19 COVID-19 complication COVID-19 complications Critical CRP D-dimer diagnose doctor domain etiologies Evidence ferritin Fungal infection help high risk high value care hospital Hospital admission hospitalized COVID-19 hospitalized COVID-19 patients identify IL-6 Immunocompromised patients indication individuals with COVID-19 Infection infections Inflammation Inpatient intensive care kidney lab Laboratory Laboratory test Laboratory testing labs LDH less Level Mortality neutrophil Neutrophil-to-lymphocyte ratio occur Other outcome Patient patients predict Prevent recommendation risk SARS-CoV-2 severe COVID-19 severe disease severity severity of COVID-19 Specific subset susceptible the patient treat Treatment troponin utility White blood cell with COVID-19 [DOI] 10.2217/fvl-2020-0316 PMC 바로가기 [Article Type] Review
Melatonin as an Add-On Treatment of COVID-19 Infection: Current StatusCommunication Published on 2021-09-202022-11-01 Journal: Diseases [Category] COVID-19, [키워드] acting addition antibody antioxidant cellular Complete conceive conducted contrary COVID-19 Critical CRP current Cytokines discharge Diseases distribution dysregulated Evidence gastrointestinal tract hospitalized COVID-19 patients Humoral immunity Immunity Infection low dose mechanism melatonin Mitochondria modulating Numerous Perspective proinflammatory cytokines radical scavenger randomized controlled study Randomized controlled trial RCT receptor repeated reported representing response Retina shown Side effects significantly status Support Symptom target the SARS-CoV-2 virus therapy for COVID-19 tissue tissues Trial [DOI] 10.3390/diseases9030064 PMC 바로가기 [Article Type] Communication
Increased sHLA-G Is Associated with Improved COVID-19 Outcome and Reduced Neutrophil Adhesion증가 된 SHLA-G는 개선 된 COVID-19 결과 및 호중구 접착 감소와 관련이 있습니다.Article Published on 2021-09-172022-08-31 Journal: Viruses [Category] SARS, 바이오마커, [키워드] activated Activation adhesion Admission Analysis Biomarker Blood CD160 changes in clinical condition clinical evolution Clinical improvement control patients controls COVID-19 COVID-19 patient COVID-19 patients E-selectin ELISA assay endothelial Endothelial cell endothelial cells Endothelium evaluated expression FGF2 HLA HLA-G hospitalized COVID-19 patient hospitalized COVID-19 patients human leukocyte antigen ICAM-1 Improved in vitro Increased infective Inflammatory Interaction inverse correlation involved leukocyte molecules neutrophil plasma Plasma levels plasma samples quantified Respiratory failure responses selectin serum significantly higher [DOI] 10.3390/v13091855 PMC 바로가기 [Article Type] Article
New-onset IgG autoantibodies in hospitalized patients with COVID-19COVID-19로 입원한 환자에서 새로 발병한 IgG 자가항체Multicenter Study Published on 2021-09-142022-09-12 Journal: Nature Communications [Category] SARS, 변종, 비임상, 임상, 진단, 치료기술, 치료법, [키워드] anti-cytokine anti-viral antibody anti-viral antibody response anti-viral antibody responses antibodies autoantibodies autoantibody autoantigen Autoantigens Autoimmune Autoimmunity cause clinical manifestations Connective tissue diseases coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokines de novo develop disorder feature healthy controls hospitalised patient Hospitalised patients hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient IgG IgG antibodies IgG antibody immune response immune responses Influenza less magnitude myositis non-structural proteins overlap pathogenic viruses Patient positively correlated proportion Protein recognizing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 proteins SARS-CoV2 seasonal coronavirus seasonal coronaviruses serum structural protein structural proteins subset Systemic sclerosis viral infection with COVID-19 [DOI] 10.1038/s41467-021-25509-3 PMC 바로가기 [Article Type] Multicenter Study
Age-Adjusted Endothelial Activation and Stress Index for Coronavirus Disease 2019 at Admission Is a Reliable Predictor for 28-Day Mortality in Hospitalized Patients With Coronavirus Disease 2019Medicine Published on 2021-09-082022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 28-day mortality 95% CI age Allogeneic Analysis blood coagulation disorders characteristic clinical prediction rule Coagulopathy Cohort complications confidence interval coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Cutoff death develop endothelial Endotheliitis Endothelium Endpoint Factor help hospitalized COVID-19 patients increased risk index log Mortality Negative predictive value Patient patients performed Positive predictive value predict Predictive Probability Retrospective study risk significantly Stem cell transplantation validation cohort [DOI] 10.3389/fmed.2021.736028 PMC 바로가기 [Article Type] Medicine
Herpes Simplex Virus Re-Activation in Patients with SARS-CoV-2 Pneumonia: A Prospective, Observational StudyArticle Published on 2021-09-072022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Herpesviridae association clinical manifestation clinically Co-infection conducted consecutive patient detectable Encephalitis event Evidence Hepatitis Herpe herpes labialis High dose Hospitalized hospitalized COVID-19 patients HSV-1 IMV incidence increased risk Infection LDH Logistic regression analysis manifestation mechanical ventilation Modena Odds ratio participant Patient patients patients with COVID-19 patients with SARS-CoV-2 PCR plasma Pneumonia positive patient Prospective re-activation SARS-CoV-2 SARS-CoV-2 pneumonia severe pneumonia significantly simplex single-center study steroid steroid treatment Steroids Support tested The effect size Tocilizumab treated use of steroid Viremia [DOI] 10.3390/microorganisms9091896 PMC 바로가기 [Article Type] Article
Bedside echocardiography to predict mortality of COVID-19 patients beyond clinical data: Data from the PROVAR-COVID studyMajor Article Published on 2021-09-062022-10-28 Journal: Revista da Sociedade Brasileira de Medicina Tropic [Category] COVID-19, MERS, SARS, [키워드] 95% CI 95%CI age Analysis association Brazil cardiac clinical variables Comorbidity COVID-19 COVID-19 patient critically ill patients death Demographic variables demographics diabete dysfunction echocardiography Ejection fraction enrolled evaluated Factor Final heart failure hospital hospitalized COVID-19 patients hypertension independent predictor intensive care Interpretation Laboratory LV dysfunction LVEF men Mortality Multivariable models Patient patients hospitalized predict Prognosis Prognostic value RV dysfunction SARS-CoV-2 significantly TAPSE Total tricuspid Univariate analysis variable ventricular with COVID-19 [DOI] 10.1590/0037-8682-0382-2021 PMC 바로가기 [Article Type] Major Article
Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBsObservational Study Published on 2021-09-022022-10-05 Journal: Human vaccines & immunotherapeutics [Category] SARS, 임상, [키워드] 28-day mortality 95% CI ACE ACE inhibitor ACE inhibitors ACEIs activity angiotensin receptor blocker Angiotensin receptor blockers ARB ARBs Belgium Case-control characterized clinical trial Combination combination treatment COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients determine drug Endothelial cell Endothelial dysfunction help hospital Hospital mortality hospitalized COVID-19 patients immunometabolism IMPROVE In-hospital maintain Mortality observational study pathogenesis of COVID-19 Propensity score receptor reduced reduction in statins survival treated Treatment unlikely Vaccine [DOI] 10.1080/21645515.2021.1920271 PMC 바로가기 [Article Type] Observational Study