Naturalizing mouse models for immunology Reviews Published on 2021-01-252022-10-05 Journal: Nature Immunology [Category] 비임상, 유전자 메커니즘, [키워드] approach condition expand fecal Genetic Immune phenotype immune system immune systems immunology Laboratory mammalian mammals Maurice Sendak mice mouse model natural selection Phylogenetic provided recent Research translational Transplant [DOI] 10.1038/s41590-020-00857-2 [Article Type] Reviews
Clocks, Viruses, and Immunity: Lessons for the COVID-19 Pandemic시계, 바이러스 및 면역: COVID-19 팬데믹에 대한 교훈Review Published on 2021-01-222022-09-10 Journal: Journal of Biological Rhythms [Category] MERS, 유전자 메커니즘, [키워드] Antiviral Biological Biological Rhythms chronobiology chronotherapy circadian clock circadian rhythm circadian rhythms CLOCK conserved COVID-19 European Evidence Host host responses host susceptibility Immunity knowledge lesson mechanisms pandemic Pathogenesis Research Research question Resilience respond rhythm SARS-CoV-2 Society Support Therapeutic strategies therapeutic strategy threat Threats translational Viral viral infection viral infections viral replication viruses [DOI] 10.1177/0748730420987669 PMC 바로가기 [Article Type] Review
Contradictions in the promotion of publishing academic and scientific journal articles, and the inability to cope with the new coronavirus (COVID-19)Commentary Published on 2021-01-122022-10-28 Journal: Antimicrobial Resistance and Infection Control [Category] COVID-19, [키워드] accelerate arise article articles Care contradiction coronavirus COVID-19 global public health Health Infectious disease Journal article knowledge New coronavirus NIH outbreak pathogen provided public health Publishing quartile question Research Research Ethics Research policy response translational [DOI] 10.1186/s13756-021-00884-0 PMC 바로가기 [Article Type] Commentary
No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor직접적인 SARS-CoV-2 스파이크 결합 수용체로서의 Basigin/CD147에 대한 증거 없음Article Published on 2021-01-112022-09-10 Journal: Scientific Reports [Category] Coronavirus, MERS, 치료기술, 치료제, [키워드] ACE2 Basigin binding Cas9 CD147 CLARITY clinical trial COVID-19 CRISPR detect entry receptor epithelial cell epithelial cells Evidence expressed form host receptor Host receptors human cell human cells human lung human lung epithelial cells hypothese in viral Infection Interaction isoform lead mechanism Pathogenesis receptor recombinant SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike Spike protein spike protein of SARS-CoV-2 susceptibility target the SARS-CoV-2 translational treat Viral viral infection viral invasion Viral proteins viral spike protein virus [DOI] 10.1038/s41598-020-80464-1 PMC 바로가기 [Article Type] Article
Role of Machine Learning Techniques to Tackle the COVID-19 Crisis: Systematic ReviewReview Published on 2021-01-112022-10-31 Journal: JMIR Medical Informatics [Category] COVID-19, [키워드] analyses applied article artificial artificial intelligence assist Care caused CINAHL complex Complication coronavirus COVID-19 COVID-19 crisis COVID-19 outbreak COVID-19 pandemic database deep learning detect detection Diagnosis Disease progression Epidemiology Health highlight Hospital stay identify intelligence intensive care item Laboratory machine learning Mortality Neural network Novel coronavirus objective organization outcome pandemic Patient patients with COVID-19 presenting problems radiological Reporting Research resource responsible Result review role SARS-CoV-2 selected systematic review technique translational Treatment variables was performed Web of Science [DOI] 10.2196/23811 PMC 바로가기 [Article Type] Review
Immunogenicity of Multiple Doses of pDNA Vaccines against SARS-CoV-2Article Published on 2021-01-062022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] Activation acute respiratory syndrome antibody Antibody Response binding candidate cellular immune responses comparable coronavirus coronavirus disease COVID-19 COVID-19 vaccine death dose doses effective elicit full-length S globular head highest immune responses Immunity immunogenicity induce interferon Limited long-lasting magnitude marker mice Multiple natural infection Neutralizing antibodies Neutralizing antibody response neutralizing antibody responses Pandemics pDNA Plasmid preclinical data Reinfection required robust S-specific antibody SARS-CoV-2 SARS-CoV-2 vaccine Serum level Support translational Undetermined Vaccine viral spike virus Wuhan, China [DOI] 10.3390/ph14010039 PMC 바로가기 [Article Type] Article
From dermatological conditions to COVID-19: Reasoning for anticoagulation, suppression of inflammation, and hyperbaric oxygen therapy피부질환부터 코로나19까지: 항응고, 염증억제, 고압산소 요법의 이유Review Published on 2021-01-012022-09-12 Journal: Dermatologic therapy [Category] SARS, 진단, [키워드] anticoagulation clinical settings Coagulation complex condition COVID-19 critically ill patients death endothelial damage generate heparin Hyperbaric oxygenation Inflammation Inflammatory Inflammatory response livedoid Lung injury macrophage activation Oxygen therapy Reasoning severe COVID-19 systemic inflammatory response thrombosis translational Vasculopathy [DOI] 10.1111/dth.14565 PMC 바로가기 [Article Type] Review
COVID-19 patients’ sera induce epithelial mesenchymal transition in cancer cells코로나19 환자 혈청, 암세포에서 상피 중간엽 전이 유도Article Published on 2021-01-012022-09-12 Journal: Cancer treatment and research communications [Category] 진단, [키워드] A549 cell applied bovine Cancer cancer cell cancer patient Cancer patients Cell cell culture experiment cells Clinical course connection consequence controls COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 pneumonia cytotoxicity dead diagnosed disease EMT epithelial experiments expression fetal Gene expression analysis healthy healthy volunteer Hospitalized Host Increased induce Infection Inflammation Interaction knowledge lack Metastasis mRNA levels nodule pathophysiology Patient patients performed persist proliferation Research SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic screened sera serum serum sample the lungs a thromboembolic processe translational VIM virus were recorded ZEB1 ZEB1, SNAIL2. [DOI] 10.1016/j.ctarc.2021.100406 PMC 바로가기 [Article Type] Article
Unpacking Pandora from Its Box: Deciphering the Molecular Basis of the SARS-CoV-2 CoronavirusReview Published on 2020-12-312022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV Basis bats cellular coronavirus coronavirus 2 COVID-19 COVID-19 pandemic Diagnosis drug feature glycosylation site Host molecular non-structural proteins novel open reading frames ORF1ab pandemic Pandora Pneumonia polyprotein pp1a pp1ab Repository respiratory RNA SARS-CoV-2 Scientific community seeking self-cleavage sequence shielding spike trimer the SARS-CoV-2 translational Transmission unique Unpacking Vaccine viral genomes virus [DOI] 10.3390/ijms22010386 PMC 바로가기 [Article Type] Review
Chemical Translational Biology-Guided Molecular Diagnostics: The Front Line To Mediate the Current SARS-CoV-2 Pandemic화학 번역 생물학 유도 분자 진단: 현재 SARS-CoV-2 유행병을 중재하는 최전선Article Published on 2020-12-112022-09-12 Journal: Chembiochem [Category] MERS, SARS, 진단, [키워드] automated benefit Chemical Chemical biology Combination coronavirus COVID-19 current Defense exceptional imperative LINE molecular Molecular diagnosis pandemic point-of-care SARS-CoV-2 severe respiratory syndrome Spread spread of COVID-19 translational [DOI] 10.1002/cbic.202000518 PMC 바로가기 [Article Type] Article