COVID-19(22) SARS-CoV-2(20) acute respiratory syndrome coronavirus(19) acute respiratory syndrome(19) molecular(16) severe acute respiratory syndrome Coronavirus(15) Infection(14) coronavirus(14) Spike protein(12) the spike protein(12) angiotensin(10) ACE2(10) RBD(10) acute respiratory syndrome coronavirus 2(10) pathway(10) the SARS-CoV-2(9) Mutation(8) Analysis(8) Receptor-binding domain(7) complex(7) free energy(7) RBD residue(7) the RBD(7) virus(7) angiotensin-converting enzyme 2(7) reduce(7) receptor(7) Contact(7) molecular dynamics(7) protein-protein interaction(7)